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Sertindole is used in the treatment of schizophrenia (mental disorder in which patient interpret reality abnormally) and mania (abnormally elevated mood)

How it works

Sertindole work by modulating the action of certain chemical messengers in the brain that affects thoughts and mood.

Common side effects

Rash, Headache, Dizziness, Fainting, Convulsion, Blurred vision, Increased appetite, Increased heart rate, Shortness of breath, Running nose, Sleepiness, Vomiting, Weakness, Orthostatic hypotension (sudden lowering of blood pressure on standing), Ejaculation disorder, Dry mouth, Nausea, Abdominal pain, Extra pyramidal symptom, Loss of appetite, Upper respiratory tract infection, Dyspepsia, Decreased white blood cell count, Paresthesia (tingling or pricking sensation), Parkinsonism, Weight gain, Fatigue, Fever, Akathisia, Anxiety, Increased liver enzymes, Itching, Increased blood pressure, Postural hypotension (low blood pressure), Rhinitis, Abdominal bloating, Cough, Dystonia, Altered taste, Drowsiness, Urinary retention, Swelling of abdomen, Increased saliva production, Respiratory tract infection, Ecg changes, Constipation, Urinary incontinence, Abnormal vision, Skin reaction, Tremor, Seizure

Available Medicine

No medicine available

Expert advice

  • Tell your doctor if you have salt-water imbalance (low magnesium in blood), diabetes, parkinsonism (a clinical syndrome characterized by tremor, bradykinesia, rigidity, and postural instability), convulsions or fits.
  • You will be checked for ECG before prescribing and while taking sertindole.  
  • You will be regularly monitored for magnesium and potassium levels, blood pressure, weight and blood sugar levels while on sertindole therapy. 
  • Do not drive or use any machinery after taking sertindole as it may cause dizziness.
  • Tell your doctor if you are pregnant, planning to become pregnant or are breastfeeding.
  • Do not take if patient is allergic to sertindole or any of its ingredients.
  • Do not take if patient with prolonged QT interval (a heart condition).
  • Do not take if patient taking medicines that are known to prolong QT interval.
  • Do not take if patient with severe cardiac or liver diseases.
  • Do not take if patient with low level of potassium in blood (hypokalemia) which is not being treated.

Content on this page was last updated on 13 February, 2017, by Dr. Varun Gupta (MD Pharmacology)