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Saroglitazar
INFORMATION ABOUT SAROGLITAZAR
Saroglitazar Uses
Saroglitazar is used in the treatment of type 2 diabetes mellitus, Non-alcoholic fatty liver disease, diabetic dyslipidemia and Noncirrhotic Non-Alcoholic Steatohepatitis.
How Saroglitazar works
Saroglitazar contains Saroglitazar, a dual action peroxisome proliferator-activated receptor (PPAR) inhibitor that aids in the management of high cholesterol, especially triglycerides, as well as blood sugar levels in people with type 2 diabetes. It acts by a unique mechanism in which it reduces the synthesis and secretion of triglycerides (a type of lipid or cholesterol in blood). It also improves insulin sensitivity of the body for better utilization of the existing insulin and hence lowers the blood sugar levels.
Common side effects of Saroglitazar
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common
Weakness, Fever, Gastritis, Headache
CONTENT DETAILS
Written By
Dr. Anuj Saini
MMST, MBBS
Reviewed By
Dr. Lalit Kanodia
MBA, MD Pharmacology
Last updated
07 Nov 2025 | 04:50 AM (UTC)
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Expert advice for Saroglitazar
  • Saroglitazar has beneficial effects in controlling both high cholesterol mainly triglycerides and sugar levels in diabetic patients.
  • It is best to take Saroglitazar before the first meal of the day.
  • You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Saroglitazar.
  • You have been prescribed Saroglitazar for the treatment of diabetic dyslipidemia.
  • Saroglitazar has beneficial effects in controlling both high cholesterol mainly triglycerides and sugar levels in diabetic patients.
  • You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Saroglitazar.
  • It is best to take Saroglitazar before the first meal of the day.
Frequently asked questions for Saroglitazar
Saroglitazar should not be taken by people who are allergic to Saroglitazar or any of its ingredients. If you are not sure, please consult your doctor.
It has been observed from clinical research conducted on Saroglitazar that there is no significant risk of weight gain in patients taking Saroglitazar. However, if a patient experiences a rapid increase in weight, any other difficulty, or fluid accumulation in the body then it should be immediately informed to the doctor for further assessment or change of therapy.
Yes, it has been found that Saroglitazar helps improve the good cholesterol or HDL-C and at the same time helps reduce the bad cholesterol like LDL, triglycerides etc. Though the effectiveness of this medicine varies from patient to patient still it has been found to be effective in controlling the high triglyceride levels in the blood. Consult your doctor before you start taking this medication.
Lifestyle changes play a major role in managing nonalcoholic steatohepatitis (NASH). A healthy body weight helps you manage this condition very effectively. Avoid taking excess salt in your diet and find ways to reduce or manage stress in your life as it increases body weight too. Practice yoga or meditation or take up a hobby. Ensure that you have a sound sleep every night as this also helps to reduce stress levels. Stop smoking and alcohol consumption. Exercise regularly and take a balanced diet that includes whole grains, fresh fruits, vegetables and fat-free products. Consult your doctor if you need any further guidance to get the maximum benefit of Saroglitazar and to keep yourself healthy.
There is no clarity on the use of Saroglitazar in pregnancy and it may be unsafe to take it in pregnancy. However, if you are pregnant or planning to conceive, consult your doctor before taking Saroglitazar. You may take it only if prescribed by your doctor.
No, it is not safe for lactating mothers to take Saroglitazar because there is no evidence of its safety for usage during breastfeeding. The other reason for not using this medicine is that it is not known whether Saroglitazar gets excreted via breast milk. Consult your doctor before taking this medicine if you are breastfeeding to make sure there is no harm to your baby.