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Retapamulin Topical



Retapamulin topical is used to treat impetigo (red sores on the skin due to bacterial infection usually affecting the face especially around nose and mouth) that occurs commonly in infants and children.

How it works

Retapamulin is an antibiotic that belongs to the class of medications called as pleuromutilins. It works by interfering with synthesis of essential proteins (protein synthesis) thereby stopping bacterial growth.

Common side effects

Skin irritation


Expert advice

  • Use retapamulin externally only on the skin. Avoid contact with eyes, mouth, lips or genital area. In case of accidental direct contact with these areas, wash immediately and contact your doctor if irritation persists.
  • Consult your doctor immediately if there is no improvement in your infection after 2 to 3 days of treatment. 
  • Stop using retapamulin and contact your doctor if you notice worsening of the infection or develop increased redness, irritation or other signs and symptoms.
  • Retapamulin should only be used for specific cases of bacterial infections as instructed by your doctor and not for any skin infections (eg. viral etc.).
  • Take precautions while using retapamulin as it may cause local skin reactions (contact dermatitis), or irritation of the eyes and mucous membranes.
  • Do not use retapamulin in children <9 months of age, unless directed by the doctor.
  • Tell your doctor if you are pregnant or planning to become pregnant or are breastfeeding.
  • Do not use if you are allergic to retapamulin or any of its ingredients.

Content on this page was last updated on 30 September, 2016, by Dr. Varun Gupta (MD Pharmacology)