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Procyclidine is used to relieve symptoms of Parkinsonism (a clinical syndrome characterized by tremor, muscular rigidity, slow and imprecise movements) due to any cause- drug-induced, age-induced, post-infections, due to compromised blood supply to brain, or unknown cause.

How it works

Procyclidine belongs to a class of drugs called as antispasmodics. It acts by preventing sudden tightening of the muscles, thereby improving muscle co-ordination, and also relieves excessive salivation associated with Parkinsonism.

Common side effects

Pus filled swelling of tooth, Agitation, Allergic skin rash, Blurred vision, Confusion, Constipation, Disorientation (alteration of mental status), Dizziness, Dry mouth, Eye tenderness, Eye pain, Hallucination, Heartburn, Stomach pain, Lightheadedness, Muscle weakness, Skin swelling, Itching, Vomiting, Stomach upset, Weakness, Fever


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Expert advice

  • Inform your doctor if you are predisposed to obstructive disease of the gut or have urinary symptoms associated with enlargement of prostate gland, rapid heartbeats, low blood pressure, increased pressure within the eyes (glaucoma), liver or kidney disease. 
  • Tell your doctor if you are consuming medications for depression, sleeplessness, allergy, urination problems, as they may interact with procyclidine.
  • Take precautions while taking procyclidine, if you are suffering from psychosis as you may experience aggravation of symptoms. 
  • Do not drive or operate machinery after taking procyclidine as it may cause dizziness and movement disorder.
  • Avoid if Patient is allergic to procyclidine or any of its ingredients. 
  • Avoid if Patient have difficulty in passing urine or stools. 
  • Avoid if Patient is suffering from a problem caused by too much pressure in the eye (closed angle glaucoma).

Frequently asked questions


Q. Is procyclidine addictive?
Drug dependence dose addiction is possible with procyclidine. Please follow your doctor's advice regarding its use.
Q. Is procyclidine a stimulant?
Procylidine can act as a stimulant in case of overdose of the drug.

Content on this page was last updated on 30 September, 2016, by Dr. Varun Gupta (MD Pharmacology)