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Prilocaine is used for local anaesthesia

How it works

Prilocaine works by blocking pain signals from the nerves to brain which decreases the sensation of pain.

Common side effects

Numbness, Slow heart rate, Cold, Decreased blood pressure, Increased blood pressure, Nausea, Sensation of warmth, Tingling sensation, Vomiting, Dizziness

Available Medicine

No medicine available

Expert advice

  • Caution is to be exercised if you have any of the following conditions: glucose-6-phosphate deficiency, congenital or idiopathic methemoglobinemia (blood disorder in which an abnormal amount of methemoglobin, a form of hemoglobin is produced).
  • Prilocaine cream is for topical use only. Do not apply near the eyes or on open wounds.
  • Take precaution while using prilocaine as there is a possibility of temporary loss of sensation and muscle function.
  • Avoid unintentional trauma or injury to the lips, tongue, cheek mucosa, or soft palate when these structures are anesthetized; postpone ingestion of food until normal function returns.
  • The effect of prilocaine may increase for up to 3 hours under occlusive dressing and may persist for 1 to 2?hour even after removal of the cream.
  • Do not drive or operate machinery as prilocaine may make you feel sleepy.
  • Do not apply cream to larger areas or for longer times than those recommended.

Frequently asked questions



Is prilocaine an amide or ester?
Prilocaine is an amide


What is prilocaine used to treat?
Prilocaine is used as a local anesthetic during superficial minor surgery and medical procedures


Does prilocaine have epinephrine?
No, Prilocaine does not have epinephrine

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Is prilocaine stronger than lidocaine?
Prilocaine is similar to lidocaine but does not cause vasodilation and has lower CNS toxicity.

Content on this page was last updated on 30 December, 2016, by Dr. Varun Gupta (MD Pharmacology)