1mg, best e pharmacy in India




Pravastatin is used along with restricted diet regimens to lower excessive fats (cholesterol and triglycerides) in blood and thus reduce the risk of development or progression of heart and blood vessel diseases. It is also used to treat hereditary high blood cholesterol (familial hypercholesterolemia) in children and to reduce increased blood lipid levels in patients receiving immunosuppressive therapy (medications that lower activity of the immune system) following an organ transplant surgery.

How it works

Pravastatin belongs to a class of medicines called HMG CoA reductase inhibitors (statins). It inhibits an enzyme called HMG-CoA reductase that is required for the production of cholesterol in the body and thereby reduces the amount of bad cholesterol (low-density lipoproteins-LDL) and increases the levels of good cholesterol (high-density lipoproteins-HDL) in the blood.

Common side effects

Nocturia (increased urge to urinate during the night), Pale red skin, Itchy rash, Abdominal pain, Constipation, Diarrhoea, Dizziness, Difficulty in urination, Hair loss, Headache, Heartburn, Indigestion, Insomnia, Itching, Nausea, Rash, Sexual dysfunction, Visual impairment, Vomiting, Fatigue


Expert advice

  • It is important that you maintain dietary restrictions while on treatment.
  • Tell your doctor if you have diabetes, an underactive thyroid gland (hypothyroidism), renal or liver diseases or muscle disorders, before starting pravastatin treatment.
  • Stop taking pravastatin and contact your doctor immediately, if you experience unexplained pain, weakness and tenderness in muscles accompanied with fever and a feeling of discomfort (malaise), fits (uncontrolled seizures) or any other medical emergency.
  • If you have history of liver disease or alcohol consumption you may need regular monitoring of liver function via blood tests while on pravastatin treatment.
  • Pravastatin should be used cautiously in children under 8 years of age.
  • Take extreme care to avoid pregnancy if you are taking pravastatin or any other statins and consult your doctor immediately if you get to know that you are pregnant.

Frequently asked questions


Q. Is pravastatin a statin drug/ statin/ blood thinner/ beta blocker/diuretic?
Pravastatin belongs to a class of medicines called HMG CoA reductase inhibitors, commonly called statins. It is not a blood thinner or a beta blocker or diuretic. It has no known effects on viscosity of blood, inhibiting beta receptors or increasing urine output.
Q. Is pravastatin the same as atorvastatin/ simvastatin/ Crestor?
No. Pravastatin, atorvastatin, simvastatin and rosuvastatin (Crestor) are different drugs belonging to same class of HMG CoA reductase inhibitors or statins. They are different drugs with similar mechanism of action.
Q. Can I take pravastatin with metformin/ aspirin/ ibuprofen/ Tylenol/ Tums/ Benadryl?
Pravastatin has no known harmful interaction with metformin, aspirin, ibuprofen, acetaminophen (Tylenol), Tums (antacids) or diphenhydramine (Benadryl)
Q. Can I take pravastatin with niacin?
Concomitant use of pravastatin with niacin should be avoided due to increased risk of developing muscle related disorders (myopathy/rhabdomyolysis).
Q. Does pravastatin cause diabetes?
Some studies suggest that statins like pravastatin may increase blood glucose is patients who are at high risk of developing diabetes.  However, it is not a reason to stop pravastatin treatment in such patients.
Q. Does pravastatin cause erectile dysfunction/ gas/ liver damage/ headaches or makes you feel tired/ joint pain/ night sweats?
Erectile dysfunction, gas, liver damage (elevation in liver enzymes), headaches and unusual tiredness (fatigue) are among the known side effects of pravastatin use. Joint pain and night sweats and not among the known side effects of pravastatin use.
Q. Does pravastatin work?
Pravastatin is used to lower the risk of heart diseases and reduce high blood cholesterol.
The effectiveness of pravastatin may vary upon individual response.
Q. Is pravastatin safe to take?
Yes. Pravastatin is safe if used at prescribed doses for the prescribed duration, as advised by your doctor.

Content on this page was last updated on 03 October, 2016, by Dr. Varun Gupta (MD Pharmacology)