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Pitofenone hydrochloride is used in combination with other painkiller medications such as sodium metamizol or diclofenac sodium and fenpiverinium bromide to provide relief from muscular contraction (spasm), menstrual cramps (spasmodic dysmenorrhea) and irritable bowel syndrome (disorder of the intestines that leads to cramps in the abdomen, gas, bloating and changes in bowel habits).

How it works

Pitofenone hydrochloride belongs to the class of drugs called as antispasmodics. It works by suppressing muscle spasms thereby relaxing the muscles. 

Common side effects

Flushing, Gastrointestinal disturbance, Decreased white blood cell count


No medicine available

Expert advice

  • Exercise caution while using pitofenone hydrochloride in infants, small children or if you are suffering from abnormal formation of blood (dyshaematopoiesis) or with unstable circulatory conditions, as in the presence of these conditions, dose should be given under medical supervision.  
  • Take extreme care while using pitofenone hydrochloride in patients suffering from bronchial asthma or chronic respiratory infections and patients with a history of allergic reactions to painkiller medications as such patients may develop shock (analgesic intolerance).
  • Do not consume alcohol when on treatment with pitofenone hydrochloride, as it may worsen its side effects.
  • Tell your doctor if you are pregnant, planning to become pregnant or are breastfeeding.
  • Do not take if allergic to pitofenone hydrochloride and any of its ingredients.
  • Do not take if suffering from kidney porphyria (disturbance of metabolism that can be seen as disorders of the skin or other organs), glucose-6-phosphate dehydrogenase deficiency present at birth, tachyarrythmias (exceeding heart rate), narrow-angle glaucoma (a condition where colored portion of the eye is pushed or pulled forward).

Content on this page was last updated on 30 September, 2016, by Dr. Varun Gupta (MD Pharmacology)