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For the treatment of type II diabetes mellitus.

How it works

The biguanide phenformin decrease ion transport processes, influence cellular metabolism and activate AMPK. Phenformin's hypoglycemic activity is related the effect it has in activating AMPK and fooling insulin sensitive cells into thinking that insulin levels are low and causing the body to use glucose as if in a state of low caloric consumption.

Common side effects

Acute pancreatitis (inflammation of pancreas), Diarrhoea, Bitter taste, Loss of appetite, Nausea, Skin reaction, Vomiting, Weight loss


No medicine available

Content on this page was last updated on 28 September, 2016, by Dr. Varun Gupta (MD Pharmacology)