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Penfluridol is used in the treatment of certain behavioral disorders (psychoses characterized by loss of touch with reality leading to false beliefs, and hearing, seeing or feeling things that are not really there).

How it works

Penfluridol belongs to a class of drugs called anti-psychotics. It acts by blocking the action of a chemical present in the brain called dopamine, thereby relieving the symptoms of psychosis.

Common side effects

Breast engorgement, Chest pain, Diarrhoea, Shortness of breath, Dizziness, Headache, Nausea, Impotence, Insomnia, Limb swelling, Movement disorder, Vomiting, Weight gain


Expert advice

  • Use with caution if you are at risk of formation of blood clots in the brain leading to interrupted blood supply and elderly patients suffering from memory loss.
  • Tell your doctor, if you have family history of blood clotting disorders. 
  • Inform your doctor if you are suffering from recurrent fits, or heart, liver, or kidney disease
  • In order to detect any cardiac problem, your doctor may record an electrocardiogram (heart tracing). 
  • Seek immediate medical attention if you experience unexplained fever, pallor or profuse sweating during penfluridol treatment.
  • Do not drive or operate machinery during penfluridol therapy as it may cause drowsiness.
  • Do not consume alcohol when on treatment with Penfluridol as it may worsen the side effects.
  • Tell your doctor if you are pregnant or breastfeeding or planning to become pregnant.

Frequently asked questions



Content on this page was last updated on 18 October, 2016, by Dr. Varun Gupta (MD Pharmacology)