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Octreotide is used in the treatment of acromegaly and bleeding esophageal varices.

How it works

Octreotide blocks the effects of certain natural hormones in the body such as serotonin and growth hormone. It also lowers the bleeding from the food pipe by constricting (narrowing) the blood vessels.

Common side effects

Diarrhoea, Abdominal pain, Nausea, Constipation, Flatulence, Headache, Increased glucose level in blood, Gallstones, Injection site reaction

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Expert advice

  • Seek medical attention if you experience disturbances in your line of vision.
  • Your thyroid function and liver function will be monitored during octreotide therapy.
  • Do not drive or operate machines while on octreotide treatment as it may cause blurred vision and headache.
  • Inform your doctor if you are taking a medicine to control your blood pressure or if you are a patient with diabetes.
  • If you are a woman of child bearing age, effective contraceptive method should be adopted during treatment with octreotide.
  • Tell your doctor if you are or planning to become pregnant or are breastfeeding.

Frequently asked questions



Is octreotide a chemo drug?
Yes, octreotide is a chemo drug, used in patients with gastro-entero-pancreatic (GEP) endocrine tumors and pituitary tumors


Is octreotide hormone/ protein?
No, octreotide is a peptide or a hormone analogue. It is a synthetic compound derived from somatostatin, a substance normally found in the human body


Is octreotide safe?
Octreotide is safe if used at prescribed doses for the prescribed duration as advised by your doctor

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Is octreotide a proton pump inhibitor/ vasopressor?
No, octreotide is neither a proton pump inhibitor nor a vasopressor


Does octreotide cause hyperglycemia?
Yes, hyperglycemia is a common side effect of octreotide treatment


Does octreotide cause hair loss and weight gain?
Yes, hair loss is a common side effect of octreotide treatment. Octreotide may cause weight gain


Does octreotide make you tired?
Yes, octreotide may make you feel tired.

Content on this page was last updated on 02 March, 2017, by Dr. Varun Gupta (MD Pharmacology)