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Octreotide

INFORMATION

Uses

Octreotide is used in the treatment of acromegaly and bleeding esophageal varices (dilated blood vessels in food pipe).
It also relieves symptoms associated with functional gastro-entero-pancreatic (GEP) endocrine tumours.

How it works

Octreotide works by blocking the effects of certain natural hormones in the body such as serotonin and growth hormone. It also decreases bleeding from food pipe by constricting (narrowing) the blood vessels.

Common side effects

Nausea, Rash, Abdominal bloating, Abdominal pain, Biliary sludge (solids precipitated from bile), Bradycardia, Gall bladder inflammation, Bile duct stone, Constipation, Decreased thyroid stimulating hormone, Diarrhoea, Discolouration of stool, Dizziness, Shortness of breath, Fall in blood sugar level, Flatulence, Glucose intolerance, Hair loss, Headache, Increased bilirubin in the blood, Increased glucose level in blood, Indigestion, Injection site pain, Itching, Loss of appetite, Sticky stools, Vomiting, Weakness

AVAILABLE MEDICINE

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Expert advice

  • Seek medical attention if you experience disturbances in your line of vision.
  • Your thyroid function and liver function will be monitored during octreotide therapy.
  • Do not drive or operate machines while on octreotide treatment as it may cause blurred vision and headache.
  • Inform your doctor if you are taking a medicine to control your blood pressure or if you are a patient with diabetes.
  • If you are a woman of child bearing age, effective contraceptive method should be adopted during treatment with octreotide.
  • Tell your doctor if you are or planning to become pregnant or are breastfeeding.

Frequently asked questions

Octreotide

Q.Is octreotide a chemo drug?
Yes, octreotide is a chemo drug, used in patients with gastro-entero-pancreatic (GEP) endocrine tumors and pituitary tumors

Q.Is octreotide hormone/ protein?
No, octreotide is a peptide or a hormone analogue. It is a synthetic compound derived from somatostatin, a substance normally found in the human body

Q.Is octreotide safe?
Octreotide is safe if used at prescribed doses for the prescribed duration as advised by your doctor

Q.Is octreotide a proton pump inhibitor/ vasopressor?
No, octreotide is neither a proton pump inhibitor nor a vasopressor

Q.Does octreotide cause hyperglycemia?
Yes, hyperglycemia is a common side effect of octreotide treatment

Q.Does octreotide cause hair loss and weight gain?
Yes, hair loss is a common side effect of octreotide treatment. Octreotide may cause weight gain

Q.Does octreotide make you tired?
Yes, octreotide may make you feel tired.


Content on this page was last updated on 05 December, 2016, by Dr. Varun Gupta (MD Pharmacology)