Nitroprusside
INFORMATION ABOUT NITROPRUSSIDE
Nitroprusside Uses
Nitroprusside is used in the treatment of Angina (heart-related chest pain), Heart Failure, coronary artery disease, hypertensive emergency and anal fissure.
How Nitroprusside works
Nitroprusside is a vasodilator. It works by relaxing the muscles in your blood vessels to help them widen and results in the lowering of blood pressure.
Common side effects of Nitroprusside
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common
Cyanide poisoning, Decreased blood pressure
CONTENT DETAILS
Last updated
08 Nov 2024 | 05:33 AM (UTC)
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Expert advice for Nitroprusside
- Nitroprusside is given as a drip (intravenous infusion) by your doctor or nurse.
- It may cause sudden lowering of blood pressure. Hence, regular monitoring of blood pressure is required during treatment.
- If there is no considerable improvement in blood pressure within 10 minutes, stop the infusion immediately.
- It may cause headaches which usually go away after a few days of continued treatment. Inform your doctor if it persists.
- Stop taking medications (prescribed for erectile dysfunction) like sildenafil or tadalafil while on treatment with Nitroprusside as it may cause low blood pressure.
- You have been prescribed Nitroprusside for the prevention and treatment of heart-related chest pain (angina).
- Eat healthy (low-fat, high-fiber, low-sodium diet), quit smoking, increase your physical activity, watch your weight and reduce stress.
- Nitroprusside may cause dizziness or sleepiness. Do not drive or do anything that requires concentration until you know how it affects you.
- Do not consume alcohol while taking Nitroprusside as it may cause increased dizziness.
- It may cause headaches which usually go away after a few days of continued treatment. Inform your doctor if it persists.
- You may develop tolerance to Nitroprusside with time, meaning that the same dose may be less effective next time. Follow the prescribed dosing schedule to avoid this.
- Stop taking medications (prescribed for erectile dysfunction) like sildenafil or tadalafil while on treatment with Nitroprusside as it may cause low blood pressure.
Frequently asked questions for Nitroprusside
Nitroprusside belongs to a class of medicines known as vasodilators. It is used to decrease the blood pressure in emergency conditions where the blood pressure is extremely high (hypertensive crisis). It is also used to maintain low blood pressure during surgical procedures in a hospital setting.
Nitroprusside widens the blood vessels (arteries and veins) which provides a better and smooth path for the blood to flow. This reduces the pressure on the walls which results in effective and significant decrease in the blood pressure.
Nitroprusside is wrapped in aluminum foil to protect it from light. This is because Nitroprusside is very sensitive to light. The solution will degrade every 4 hours if left unprotected. On the contrary, covering it with aluminum foil makes it stable for around 24 hours.
Nitroprusside may cause side effects like low blood pressure and cyanide poisoning. Additionally, you may also notice abdominal pain, sweating, dizziness, headache, muscle twitching and nausea. However, these are usually not bothersome but if any of these side effects worry you or persist for a longer duration of time, please consult your doctor. Your doctor will suggest ways to manage or prevent these side effects.
Nitroprusside is extremely sensitive to light. If left open, its chemical composition changes rapidly and the color may change from brown to blue or green. If left unprotected, 20% of the solution will deteriorate every 4 hours even in glass bottles. Therefore, it is necessary to prevent exposure of Nitroprusside to any kind of light, especially fluorescent light.