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Mosapride is used for the treatment of heartburn, nausea, acid reflux and vomiting associated with chronic gastritis (long-standing swelling, redness, and irritation of inner lining of stomach), and also to accelerate gastric emptying in patients undergoing barium enema (x-ray examination).

How it works

Mosapride belongs to class of drugs called selective serotonin (5HT4) antagonists. It is a prokinetic drug which promotes the forward flow of stomach contents including stomach acid and prevents their reflux into the food pipe thereby preventing heartburn.

Common side effects

Vomiting, Nausea, Abdominal pain, Constipation, Diarrhoea, Dizziness, Headache, Insomnia


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Expert advice

• Exercise caution while taking mosapride if you have jaundice or heart diseases. 
• Never take more than the recommended dose of mosapride as it can adversely affect normal heartbeat.
• Do not drink alcohol while on mosapride treatment as they can cause excessive drowsiness.
• Tell your doctor if you are pregnant or planning to become pregnant or breastfeeding.
• Patients allergic to mosapride or any of its ingredients should not take mosapride.
• Patients with bleeding ulcer in the stomach or gut should not take mosapride.
• Patients with gut obstruction should not take mosapride.
• Breastfeeding women should not take mosapride.

Content on this page was last updated on 30 September, 2016, by Dr. Varun Gupta (MD Pharmacology)