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    Information about Lurasidone

    Lurasidone uses

    Lurasidone is used in the treatment of schizophrenia.

    How lurasidone works

    Lurasidone work by modulating the action of certain chemical messengers in the brain that affects thoughts.

    Common side effects of lurasidone

    Nausea, Vomiting, Weight gain, Sleepiness, Dryness in mouth, Dyspepsia, Parkinsonism, Akathisia, Anxiety, Stomach discomfort, Restlessness, Abdominal pain upper, Agitation, Insomnia (difficulty in sleeping), Increased saliva production
    Content Details
    Written By
    Dr. Anuj Saini
    Reviewed By
    Dr. Ashish Ranjan
    MD (Pharmacology), MBBS
    Last updated on:
    06 Nov 2019 | 10:43 AM (IST)
    Want to know more?
    Read Our Editorial Policy

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    Expert advice for Lurasidone

    • Lurasidone helps treat schizophrenia.
    • It has a lower risk of causing weight gain and changes to cholesterol, blood sugar, and heart rhythm as compared to other similar medicines.
    • Use caution while driving or doing anything that requires concentration as Lurasidone can cause dizziness and sleepiness.
    • Do not consume alcohol while on treatment with this medicine as it may worsen the side effects.
    • Inform your doctor if you notice any abnormal or uncontrolled movements.
    • Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
    • Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
    • Do not stop taking this medicine without talking  to your doctor first as it may cause worsening of symptoms.

    Frequently asked questions for Lurasidone


    Q. Can Lurasidone be used during pregnancy?

    Lurasidone should be avoided during pregnancy unless this has been prescribed by your doctor. Your doctor will monitor your baby closely after birth because giving Lurasidone during the last 3 months to the mother may cause shaking, sleepiness, agitation, breathing problems, difficulty in feeding and muscle stiffness and/or weakness in the baby.

    Q. What monitoring is required during treatment with Lurasidone?

    Lurasidone may cause an increase in blood sugar levels in diabetic patients or those having risk factors for diabetes. It may also decrease white blood cell count and increase prolactin, cholesterol and triglyceride levels. Therefore, during treatment with Lurasidone, your doctor may get blood tests done to check for blood sugar levels, blood cell counts, prolactin levels (hormone) and cholesterol and triglyceride levels.

    Q. How should Lurasidone be taken?

    Lurasidone should be swallowed whole with water in order to mask the bitter taste. You should take it during meals or just after having meals as this helps the body to take up the medicine and allows it to work better. Try to take it at the same time every day, so that you remember to take it.

    Q. Does Lurasidone cause weight gain?

    Weight gain is a common side effect of Lurasidone, though not everyone is affected. If you experience weight gain on taking Lurasidone, talk to your doctor or a nutritionist. Eating a healthy diet and exercising regularly can help you maintain your weight.

    Q. How long does Lurasidone take to work?

    Lurasidone does not show any immediate improvement. It may take several days to weeks to notice improvement in symptoms. The patient is continuously monitored during this time.

    Q. What should be avoided while taking Lurasidone?

    Alcohol should be avoided while taking Lurasidone since taking both together may cause severe side effects. In addition to that, you should not drink grapefruit juice while on Lurasidone since it affects the way it works.

    Q. What is the most important information I should know about Lurasidone?

    Lurasidone can cause increased risk of death in elderly people who have confusion, memory loss or have lost touch with reality (dementia-related psychosis). It is important to know that Lurasidone may increase suicidal thoughts or behavior in some children, teenagers, and young adults within the first few months of treatment and when the dose is changed.

    Q. Does Lurasidone cause dizziness?

    Yes, Lurasidone may cause dizziness, sleepiness and vision problems. If you experience any of these symptoms, you should avoid driving or using heavy machinery.

    Content on this page was last updated on 06 November, 2019, by Dr. Varun Gupta (MD Pharmacology)