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Lubiprostone is used in the treatment of constipation

How it works

Lubiprostone increases secretion of fluid in the intestines, which increases motility of the intestine, thereby facilitating the passage of stool.

Common side effects

Headache, Nausea, Abdominal pain, Flatulence, Abdominal distension, Diarrhoea

Available Medicine

Expert advice

  • Lubiprostone should preferably be taken with meals to reduce symptoms of nausea.
  • Seek medical attention if you experience severe diarrhea, breathlessness (dyspnea) or difficulty in breathing, chest pain, tightness in chest during treatment.
  • You should be thoroughly examined to confirm the absence of obstruction (e.g. gall stones, hernia, Crohn's disease, diverticulitis, polyps, impacted bowel movement etc.) before starting lubiprostone treatment.
  • Lubiprostone is not recommended in children under 18 years of age.
  • Tell your doctor if you are pregnant or planning to become pregnant or are breastfeeding.

Frequently asked questions


Q. Is lubiprostone a steroid?
No. Lubiprostone does not have a chemical structure or mechanism of action similar to steroids.

Content on this page was last updated on 11 January, 2017, by Dr. Varun Gupta (MD Pharmacology)