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    Information about Leuprolide/Leuprorelin

    Leuprolide/leuprorelin uses

    Leuprolide/Leuprorelin is used for prostate cancer, endometriosis, uterine fibroids and precocious puberty. It is also used to reduce the thickness of the endometrium of the uterus in preparation for surgery.

    How leuprolide/leuprorelin works

    Leuprolide/Leuprorelin is a hormone similar to the one produced by a hypothalmus gland in the brain. It works by decreasing the blood levels of testosterone in males.

    Common side effects of leuprolide/leuprorelin

    Decreased libido, Testicular atrophy, Increased sweating, Fatigue, Muscle weakness, Erectile dysfunction, Bone pain, Hot flashes, Injection site reaction
    Content Details
    Written By
    Dr. Anuj Saini
    Reviewed By
    Dr. Ashish Ranjan
    MD (Pharmacology), MBBS
    Last updated on:
    16 Oct 2019 | 01:30 PM (IST)
    Want to know more?
    Read Our Editorial Policy

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    Expert advice for Leuprolide/Leuprorelin

    • Leuprolide/Leuprorelin helps in the treatment of locally advanced or metastatic prostate cancer.
    • It may also be used to treat endometriosis and uterine fibroids.
    • It is given as an injection either under the skin or into a muscle.
    • It may cause dizziness and visual disturbances. Don't drive or do anything that requires mental focus until you know how it affects you.
    • It will cause menstrual periods to stop. Periods will resume 7-12 weeks after the final injection. Consult your doctor if you experience menstrual bleed despite treatment. 
    • Use non-hormonal methods of contraception such as condoms to prevent pregnancy during treatment, as this medicine may be harmful to a developing baby.
    • Long term treatment may lead to bone loss and a higher risk of bone fractures, especially if you are a heavy drinker, a smoker, or have a family history of osteoporosis.

    Frequently asked questions for Leuprolide/Leuprorelin


    Q. What is Leuprorelin used for?

    Leuprorelin is used in the treatment of advanced and/or metastatic prostate cancer. It is also used to treat central precocious puberty (condition causing children to enter puberty too soon resulting in faster than normal bone growth and development of sexual characteristics), endometriosis (a condition in which the endometrium lines the uterus grows excessively and causes pain, heavy or irregular [periods], and other symptoms), anemia (lower than normal red blood cells count) due to uterine fibroids (noncancerous growth in the uterus). Leuprorelin may be used for infertility, breast cancer and before intra-uterine surgery

    Q. What is leuprorelin acetate?

    Leuprorelin belongs to a class of medicines called gonadotropin-releasing hormone (GnRH) agonists

    Q. Can I take ibuprofen/ Tylenol (paracetamol)/ Benadryl (anti-cough preparation) with Lupron/leuprorelin?

    There are no known drug interactions of leuprorelin with ibuprofen/ Tylenol (paracetamol)/ Benadryl.

    Content on this page was last updated on 16 October, 2019, by Dr. Varun Gupta (MD Pharmacology)