Ivermectin + Albendazole
Information about Ivermectin + Albendazole
Ivermectin + albendazole uses
Ascariasis, Trichuriasis, Strongyloidiasis, Enterbiasis. Onchocerciasis, Elephantiasis.
How ivermectin + albendazole works
Ivermectin selectively binds and with high affinity to glutamate-gated and GABA (GABA)-gated chloride ion channels. This increases the permeability of the cell membrane to chloride ions leading to hyperpolarisation of muscles and nerve cells, thus ultimately causing paralysis and death of the parasites. Albendazole causes degenerative alterations in the intestinal cells of the worm by inhibiting polymerisation or assembly of tubules into microtubules. The loss of the cytoplasmic microtubules leads to impaired uptake of glucose by the larval and adult stages of the susceptible parasites and depletes their glycogen stores. Degenerative changes in the endoplasmic reticulum, the mitochondria of the germinal layer and subsequent release of lysosomes result in decreased production of ATP (ATP), which is the energy required for the survival of the helminth. Due to diminished energy production, the parasite is immobilised and eventually dies.
Common side effects of ivermectin + albendazole
Postural hypotension (low blood pressure), Rash, Joint pain, Diarrhoea, Dizziness, Fever, Itching, Muscle pain, Nausea, Urticaria, Vomiting, Weakness.
Available Medicine for Ivermectin + Albendazole
- ₹20 to ₹28Mankind Pharma Ltd3 variant(s)
- ₹30Zydus Cadila1 variant(s)
- ₹20 to ₹28Mankind Pharma Ltd2 variant(s)
- ₹33Abbott India Ltd1 variant(s)
- ₹24Cipla Ltd1 variant(s)
- ₹20Canvarzys Pharmaceuticals1 variant(s)
- ₹20 to ₹26Lincoln Pharmaceuticals Ltd2 variant(s)
- ₹18 to ₹23Klar Sehen Pvt Ltd2 variant(s)
- ₹17 to ₹25Micro Labs Ltd2 variant(s)
- ₹19Abbott India Ltd1 variant(s)