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Itolizumab is used to treat patients with chronic plaque psoriasis (patches of thick, red, scaly skin) of active, moderate to severe grade.

How it works

Itolizumab belongs to the class of medications known as anti-CD6 monoclonal antibodies. It works by inhibiting CD6 cells (immune system component) resulting into reduced levels of cytokines and T-cell infiltration at the site of inflammation thereby reducing inflammation.

Common side effects

Irritation of ear, Allergic skin rash, Dizziness, Flushing, Gastrointestinal disturbance, Headache, Decreased white blood cell count, Nausea, Diarrhoea


Expert advice

  • Inform your doctor if you are have any active infection including active and/or latent (inactive) tuberculosis.
  • Tell your doctor if you are pregnant or planning to become pregnant or are breastfeeding.
  • Do not take if allergic to itolizumab or any of its ingredients.
  • Do not take if less than 18 years.

Content on this page was last updated on 30 September, 2016, by Dr. Varun Gupta (MD Pharmacology)