![](data:image/svg+xml,%3Csvg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 124px 36px"%3E%3C/svg%3E)
![](data:image/svg+xml,%3Csvg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 22px 22px"%3E%3C/svg%3E)
![](data:image/svg+xml,%3Csvg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 24px 24px"%3E%3C/svg%3E)
Isosorbide Dinitrate
INFORMATION ABOUT ISOSORBIDE DINITRATE
Isosorbide Dinitrate Uses
Isosorbide Dinitrate is used in the treatment of Angina (heart-related chest pain), Heart Failure, coronary artery disease, hypertensive emergency and anal fissure.
How Isosorbide Dinitrate works
Isosorbide Dinitrate is a nitrate. It works by relaxing the blood vessels which decreases the oxygen demand of the heart and reduces its workload, thereby preventing/treating attacks of angina (chest pain).
Common side effects of Isosorbide Dinitrate
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common
Headache
CONTENT DETAILS
![](data:image/svg+xml,%3Csvg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 48 48"%3E%3C/svg%3E){kind=small}
Written By
Dr. Anuj Saini
MMST, MBBS
Reviewed By
Dr. Rajeev Sharma
MBA, MBBS
Last updated
08 Nov 2024 | 05:33 AM (UTC)
![](data:image/svg+xml,%3Csvg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 90px 75px"%3E%3C/svg%3E)
We provide you with authentic, trustworthy and revelant information
Read our editorial policy
Medicine brands for Isosorbide Dinitrate
Expert advice for Isosorbide Dinitrate
- Eat healthy (low-fat, high-fiber, low-sodium diet), quit smoking, increase your physical activity, watch your weight and reduce stress.
- Isosorbide Dinitrate may cause dizziness or sleepiness. Do not drive or do anything that requires concentration until you know how it affects you.
- Do not consume alcohol while taking Isosorbide Dinitrate as it may cause increased dizziness.
- It may cause headaches which usually go away after a few days of continued treatment. Inform your doctor if it persists.
- You may develop tolerance to Isosorbide Dinitrate with time, meaning that the same dose may be less effective next time. Follow the prescribed dosing schedule to avoid this.
- Stop taking medications (prescribed for erectile dysfunction) like sildenafil or tadalafil while on treatment with Isosorbide Dinitrate as it may cause low blood pressure.
- You have been prescribed Isosorbide Dinitrate for the prevention and treatment of heart-related chest pain (angina).
- Eat healthy (low-fat, high-fiber, low-sodium diet), quit smoking, increase your physical activity, watch your weight and reduce stress.
- Isosorbide Dinitrate may cause dizziness or sleepiness. Do not drive or do anything that requires concentration until you know how it affects you.
- Do not consume alcohol while taking Isosorbide Dinitrate as it may cause increased dizziness.
- It may cause headaches which usually go away after a few days of continued treatment. Inform your doctor if it persists.
- You may develop tolerance to Isosorbide Dinitrate with time, meaning that the same dose may be less effective next time. Follow the prescribed dosing schedule to avoid this.
- Stop taking medications (prescribed for erectile dysfunction) like sildenafil or tadalafil while on treatment with Isosorbide Dinitrate as it may cause low blood pressure.
Frequently asked questions for Isosorbide Dinitrate
Isosorbide Dinitrate belongs to a group of medicines called organic nitrates. Isosorbide Dinitrate is used to prevent and treat angina pectoris and as an adjunctive treatment in severe acute or chronic congestive cardiac failure.
Isosorbide Dinitrate works by widening the blood vessels in your heart to allow an increased amount of blood flow to areas which need it.
No, Isosorbide Dinitrate does not lower heart rate. However, in some cases, one may experience reflex tachycardia (fast heart rate) while using nitrates such as Isosorbide Dinitrate.
Yes, Isosorbide Dinitrate lowers blood pressure. This medicine widens the blood vessels and decreases the resistance in them, causing a fall in blood pressure. This fall in blood pressure may in turn decrease the heartbeat which can lead to angina. This medicine should be avoided in people who already have low blood pressure. Discuss with your doctor if you have any concerns.
No, you should not take sildenafil along with Isosorbide Dinitrate. Both these medicines lower blood pressure and belong to the same class. Taking these two medicines together may cause significant decrease in blood pressure which can cause fainting or even a heart attack. Along with this, avoid taking other medicines which belong to the same class such as vardenafil and tadalafil.