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Hydroxocobalamin provides Vitamin B12 supplementation for the treatment of illnesses caused by a lack of Vitamin B12 like poor sight due to toxins such as tobacco (tobacco amblyopia), deterioration of the optic nerve resulting in loss of vision (Leber’s atrophy) and in the treatment/prevention of addisonian pernicious anemia and other anemias due to deficiency of Vitamin B12 .

How it works

Hydroxocobalamin belongs to group of medicines called as vitamin supplements. It works by providing additional vitamin B12 in the body which is required for metabolism and energy production, growth and development of various cells in body and needs to be provided during its deficiency.

Common side effects

Allergy, Flushing, Anaphylactic reaction, Dark colored urine, Skin redness


No medicine available

Expert advice

  • You will be regularly monitored for serum potassium levels and platelet count during therapy to avoid hypokalemia (reduced potassium in body) and thrombocytosis (excess of platelet cells in body).
  • Tell your doctor if you are pregnant, planning to become pregnant or are breastfeeding.
  • Do not take if allergic to hydroxocobalamin or any of its ingredients.

Frequently asked questions


Q. Is hydroxocobalamin the same as cyanocobalamin and methylcobalamin?
Hydroxocobalamin is obtained by biosynthesis of vitamin by bacteria and archaea whereas cyanocobalamin is the semi-synthetic form of the vitamin, produced from bacterial hydroxocobalamin. In the body, cyanocobalamin is converted to methylcobalamin.

Q. hat is hydroxocobalamin injection form used for?
Hydroxocobalamin injectable form is used to treat low levels of vitamin B12 and anemia.
Q.Does hydroxocobalamin need to be kept in the fridge?
Hydroxocobalamin is stored at or below 25°C but it is not refrigerated.

Q. How does hydroxocobalamin work in cyanide poisoning?
Hydroxocobalamin is used as an antidote to cyanide poisoning which works by helping body cells to convert cyanide to a form that can be removed from the body through urination.

Content on this page was last updated on 30 September, 2016, by Dr. Varun Gupta (MD Pharmacology)