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Homatropine is used to widen the pupil before eye examination, before and after certain eye surgeries, and to treat certain eye conditions.

How it works

Homatropine belongs to a class of drugs called anticholinergics. It blocks the chemical called acetylcholine, which then relaxes the muscles of the eye and causes the pupil to widen.

Common side effects

Blurred vision, Tingling sensation in eye, Burning sensation in eye, Eye irritation, Increased intraocular pressure, Vascular complications


Expert advice

  • Do not apply homatropine while wearing contact lenses. Leave a gap at least 15 to 12 mins after applying this medicine before you wear your contact lenses.
  • Homatropine may make your eyes more sensitive to sunlight. Take necessary precautions like wearing sunglasses may help to protect your eyes from bright sunlight.
  • Use homatropine with caution if you are an elderly patient or a child as you may be more sensitive to its effects; seek medical attention if you develop any serious side effects.
  • Do not drive or operate machinery as homatropine may cause blurred vision.

Frequently asked questions


Q. Is homatropine the same as atropine?
No. Homatropine is not same as atropine.
Q. Is homatropine hydrocodone lean/narcotic/ antihistamine?
Homatrpine is not hydrocodone lean or narcotic or antihistamine.
Q. Does hydrocodone homatropine syrup contain acetaminophen?
No. hydrocodone homatropine syrup does not contain acetaminophen.
Q. Can I take hydrocodone homatropine syrup/ Tylenol/ ibuprofen with Benadryl?
While using homatropine, you need to consult your doctor for other medication use with homatropine.
Q. Does homatropine make you sick/high/sleepy?
Limited duration use of homatropine does not make you sick or high or sleepy. However long term use may cause such side effects, hence homatropine should be taken as per doctor’s advice only.

Content on this page was last updated on 30 September, 2016, by Dr. Varun Gupta (MD Pharmacology)