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Histamine is used in the treatment of acidity, heartburn, intestinal ulcers and stomach ulcers.

Common side effects

Fatigue, Drowsiness, Headache, Constipation, Diarrhoea, Muscle pain

Available Medicine

No medicine available

Expert advice

  • Histamine is a well tolerated and safe medicine with a very low incidence of side effects.
  • Take Histamine before going to bed if you are taking this medicine once a day as it is very effective in controlling stomach acid released in the midnight.
  • If you are also taking an antacid, take it two hours before or after taking Histamine.
  • Avoid taking soft drinks, citrus fruits like orange and lemon, which can irritate the stomach and increase acid secretion.
  • Inform your doctor if you do not feel better after taking Histamine for two weeks or 14 days as you may be suffering from some other problems.
  • Inform your doctor if you have ever been diagnosed with kidney or liver disease. Dose of your medicine may need to be adjusted.

Frequently asked questions



Can I take histamine for a cold/ heat rash/ hives/ mosquito bites/ bug bites?
Always follow the instructions of doctor regarding the use of histamine


Does Histamine cause blood pressure/ fever/ pain/ weight gain/constipation/ drowsiness / edema / vasodilation or vasoconstriction/ bronchodilation?
Histamine may cause these side effects. Call your doctor if you experience any unusual problems during your treatment.


Is histamine a Hormone/Protein/ Vasodilator/ cytokine/ neurotransmitter/ agonist/ amino acid/ inhibitory or excitatory/ an enzyme/ a monoamine?
Histamine is a monoamine and not a hormone, protein, enzyme or amino acid. Histamine is an excitatory vasodilator and not a cytokine or neurotransmitter or inhibitory agonist

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Can I take Histamine with amoxicillin /prednisolone/ ibuprofen/ antibiotics/ amoxicillin / citalopram / paracetamol /singulair /warfarin / sertraline?
Histamine may interact with these medications. Kindly follow doctors instructions

Content on this page was last updated on 26 April, 2017, by Dr. Varun Gupta (MD Pharmacology)