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    Glimepiride + Metformin + Voglibose

    Information about Glimepiride + Metformin + Voglibose

    Glimepiride + metformin + voglibose uses

    Glimepiride+Metformin+Voglibose is used in the treatment of type 2 diabetes mellitus.

    How glimepiride + metformin + voglibose works

    This is a combination of three antidiabetic medicines: Glimepiride, metformin and voglibose. They work by different mechanisms to provide better control of blood sugar when single or dual therapy is not effective. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas to lower the blood glucose. Metformin is a biguanide which lowers glucose production in the liver, delays glucose absorption from intestines and increases the body's sensitivity to insulin. Voglibose is an alpha-glucosidase inhibitor which prevents breakdown of complex sugars into simple sugars such as glucose. This prevents the blood glucose levels from rising to very high levels after meals.

    Common side effects of glimepiride + metformin + voglibose

    Hypoglycemia (low blood sugar level), Nausea, Diarrhea, Taste change, Flatulence, Stomach pain, Headache, Skin rash, Respiratory tract infection
    Content Details
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    Written By
    Dr. Arpit Bhatnagar
    PGDHHM - Hospital and Healthcare Management, BDS
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    Reviewed By
    Dr. Shilpa Garcha
    Writing in Medical Sciences, Medical Writing, Advanced PG Diploma in Clinical Research
    Last updated on:
    14 May 2019 | 02:46 PM (IST)
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    Expert advice for Glimepiride + Metformin + Voglibose

    • Take it with food to lower your chance of having an upset stomach.
    • It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. Carry a sugar source with you for immediate relief.
    • Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

    Frequently asked questions for Glimepiride + Metformin + Voglibose

    Glimepiride + Metformin + Voglibose

    Q. What is Glimepiride+Metformin+Voglibose?

    Glimepiride+Metformin+Voglibose is a combination of three medicines: Glimepiride, Metformin and Voglibose. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves the blood glucose levels in adults when taken along with proper diet and regular exercise. Glimepiride lowers the blood glucose levels by increasing the release of insulin from the pancreas. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. Voglibose is an alpha-glucosidase inhibitor which lowers the postprandial (after meals) glucose levels in the body. This combination is not indicated for the treatment of Type 1 DM.

    Q. What are the possible side effects of Glimepiride+Metformin+Voglibose?

    The use of Glimepiride+Metformin+Voglibose is associated with common side effects like hypoglycemia (low blood sugar level), nausea, diarrhea, altered taste, flatulence, stomach pain, headache, skin rash and respiratory tract infection.

    Q. Are there any specific conditions in which Glimepiride+Metformin+Voglibose should not be taken?

    The use of Glimepiride+Metformin+Voglibose should be avoided in patients with known allergy to any of the components or excipients of this medicine. The use of this medicine is also avoided in patients with moderate to severe kidney disease and in patients with inflammatory bowel disease, colonic ulcerations and underlying metabolic acidosis including diabetic ketoacidosis.

    Q. Is it safe to take alcohol while I am also taking Glimepiride+Metformin+Voglibose?

    No, it is not safe to take Glimepiride+Metformin+Voglibose along with alcohol. It may lower your low blood sugar levels (hypoglycemia) and can increase the chances of lactic acidosis.

    Q. Can the use of Glimepiride+Metformin+Voglibose cause hypoglycemia?

    Yes, the use of Glimepiride+Metformin+Voglibose can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate, and feeling anxious or shaky. It happens more often if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with it. So, regular monitoring of blood sugar level is important. Always keep glucose tablets, honey or fruit juice with you.

    Q. What are the instructions for the storage and disposal of Glimepiride+Metformin+Voglibose?

    Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

    Content on this page was last updated on 14 May, 2019, by Dr. Varun Gupta (MD Pharmacology)