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    Information about Flupirtine

    Flupirtine uses

    Flupirtine is used in treatment of musculo-skeletal pain, headache, nerve pain, post operative pain and pain during menstruation.

    How flupirtine works

    Flupirtine decreases the perception of pain by blocking the transmission of pain signals to the brain.

    Common side effects of flupirtine

    Fatigue, Dizziness, Drowsiness, Nausea, Dryness in mouth, Bloating, Itching, Tremor
    Content Details
    Written By
    Dr. Sakshi Sharma
    Reviewed By
    Dr. Ashish Ranjan
    MD (Pharmacology), MBBS
    Last updated on:
    18 Feb 2020 | 05:21 PM (IST)
    Want to know more?
    Read Our Editorial Policy

    Available Medicine for Flupirtine

    • ₹92 to ₹178
      Sun Pharmaceutical Industries Ltd
      2 variant(s)
    • ₹103 to ₹224
      Lupin Ltd
      2 variant(s)
    • ₹89 to ₹147
      Sun Pharmaceutical Industries Ltd
      2 variant(s)
    • ₹92
      Intas Pharmaceuticals Ltd
      1 variant(s)
    • ₹103
      Lupin Ltd
      1 variant(s)
    • ₹208
      Lupin Ltd
      1 variant(s)
    • ₹86
      Aristo Pharmaceuticals Pvt Ltd
      1 variant(s)
    • ₹84
      Intas Pharmaceuticals Ltd
      1 variant(s)
    • ₹96
      Icon Life Sciences
      1 variant(s)
    • ₹70
      Wockhardt Ltd
      1 variant(s)

    Expert advice for Flupirtine

    • Flupirtine is given when pain killers (NSAIDs) cannot be given due to gastric damage caused by them.
    • Inform your doctor before starting Flupirtine if
      • You have an underlying liver disease
      • You take alcohol regularly
      • You are pregnant or planning to get pregnant or breastfeeding
    • Get your liver function tests done before starting Flupirtine and follow up tests every week while you are taking the medicine.
    • Stop taking Flupirtine and immediately inform your doctor if you get any symptoms of liver disease like nausea, vomiting, stomach pain or yellow colored urine.

    Frequently asked questions for Flupirtine


    Q. Is Flupirtine beneficial in the treatment of fibromyalgia?

    Yes, Flupirtine is seen to be beneficial in the treatment of fibromyalgia in some clinical studies, however, Flupirtine is yet to get formal regulatory approval for this condition. Fibromyalgia is a disease that is characterized by musculoskeletal pain, fatigue, and depression.

    Q. What is the benefit of using Flupirtine with paracetamol?

    Both Flupirtine and paracetamol help in relieving pain but they work in entirely different ways. When paracetamol is given with Flupirtine, pain relief is better as compared to single drug use. However, both can cause liver toxicity, so monitoring of liver function is very important when taken together.

    Q. Does Flupirtine cause liver toxicity?

    Yes, Flupirtine causes liver toxicity. Use of Flupirtine is contraindicated in patients with an underlying liver disease.

    Q. Can Flupirtine be used for the treatment of osteoarthritis pain?

    Flupirtine can be used for the relief of pain associated with osteorthritis and post orthopedic surgery pain. It is especially useful for patients who cannot take NSAIDs because of the risk of NSAID-induced gastritis.

    Q. Does use of Flupirtine cause green discoloration of urine?

    There have been case reports that Flupirtine causes green discoloration of urine. However, this is not a very commonly seen effect. Inform your doctor if you experience this symptom.

    Q. Is Flupirtine useful in the treatment of epilpesy?

    Flupirtine is not approved for the treatment of epilepsy. However, a few animal studies have shown a beneficial effect of Flupirtine for treating epilepsy and this effect is still being explored.

    Q. Would I experience any withdrawal symptoms once I stop using Flupirtine?

    Yes, you can experience withdrawal symptoms once you stop using Flupirtine like sweating, tremor, and mood alterations with long term use of Flupirtine. Inform your doctor if you have these symptoms.

    Content on this page was last updated on 18 February, 2020, by Dr. Varun Gupta (MD Pharmacology)