Information about Eplerenone

Eplerenone Uses

Eplerenone is used in the treatment of Hypertension (high blood pressure) and Edema. It treats oedema (fluid overload) associated with heart, liver, kidney or lung disease.

How Eplerenone works

Eplerenone is a potassium-sparing diuretic. It lowers blood pressure and swelling by removing the extra water and electrolytes from the body without loss of potassium.

Common side effects of Eplerenone

Increased potassium level in blood, Increased creatinine level in blood
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MD Pharmacology, MBBS
Last updated
15 Jun 2020 | 12:47 PM (UTC)

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Available Medicine for Eplerenone

PlanepLupin Ltd
400 to ₹7113 variant(s)
EptusGlenmark Pharmaceuticals Ltd
182 to ₹6083 variant(s)
ExentaAlembic Pharmaceuticals Ltd
226 to ₹3862 variant(s)
EplehefSun Pharmaceutical Industries Ltd
204 to ₹3452 variant(s)
ExiniaRPG Life Sciences Ltd
154 to ₹3312 variant(s)
EpnoneMSN Laboratories Ltd
216 to ₹3902 variant(s)
EplecardCadila Pharmaceuticals Ltd
317 to ₹4002 variant(s)
EzuricAlkem Laboratories Ltd
247 to ₹3192 variant(s)
EpliniceTorrent Pharmaceuticals Ltd
2701 variant(s)
EpleriteCipla Ltd
180 to ₹3252 variant(s)

Expert advice for Eplerenone

  • Eplerenone helps remove fluid from your body when used with other drugs.
  • It can make you feel dizzy for the first few days. Do not drive or do anything requiring concentration until you know how Eplerenone affects you.
  • It may increase the level of potassium in your blood. Avoid taking potassium supplements and potassium-rich foods such as banana and broccoli.
  • Your doctor will regularly check your kidney function and the amount of potassium in your blood while you are on this medicine.
  • Notify your doctor if you experience dizziness, diarrhea, vomiting, fast or irregular heartbeat, swelling in feet, or difficulty breathing.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Frequently asked questions for Eplerenone


Q. What does Eplerenone do? Is it a beta blocker or a diuretic?

Eplerenone is a potassium-sparing diuretic. It is prescribed with other medicines to control increased blood pressure and to treat heart failure in patients who have had a heart attack. It is not a beta blocker but mineralocorticoid receptor blocker.

Q. How long does Eplerenone take to work?

Eplerenone controls high blood pressure but does not cure it. You may not see any improvement because high blood pressure does not have any symptoms. But, if you get your blood pressure checked, you may notice a change within 2 weeks of starting Eplerenone. However, the medicine may take 4 weeks or longer to show its maximum benefits.

Q. Does Eplerenone cause erectile dysfunction?

No, Eplerenone does not cause erectile dysfunction. Eplerenone does not have any effect on fertility, in both males and females.

Q. My blood pressure is now controlled, still the doctor has asked me to continue the treatment. Can I stop Eplerenone?

No, you should not stop Eplerenone. If your doctor has advised you to continue treatment, keep taking it. Eplerenone does not cure blood pressure, but keeps the blood pressure in control. Therefore, keep taking the medicine even if your blood pressure is controlled. Stopping it may make your condition worse and you may have unwanted side effects.

Q. Eplerenone is a potassium-sparing diuretic. Does this mean that I will have more potassium in my body? Will it be beneficial for me?

Potassium-sparing diuretic are those medicines which increase the urination without causing any loss in potassium levels. Eplerenone allows sodium loss by body in exchange for potassium which is retained. It may result in an increase in the levels of potassium. Therefore, your doctor may monitor your potassium levels continuously. You may need to get it measured before starting Eplerenone, within the first week and one month after the start of treatment or after a change in dose. Potassium levels above normal range are not good for you or anyone.

Q. Does Eplerenone have any effect on the blood sugar levels?

Although it is not very common, but Eplerenone may increase your blood sugar levels. Therefore, it is important that you keep a regular check on your blood sugar levels if you are a diabetic. The use of Eplerenone should be avoided in patients who have type 2 diabetes along with some kidney problem in which the patient loses protein (albumin) in very small quantities in urine.

Q. I had been using Losartan for quite some time and was tolerating it well. Now my doctor has prescribed me Eplerenone along with Hydrochlorothiazide. I want to know why he just could not add Eplerenone with Losartan?

It could be possible that Losartan was not able to control your blood pressure adequately. Therefore, your doctor may have suggested an alternative medicine for blood pressure control (Eplerenone), but Eplerenone when taken with Losartan can enhance the chances of raised potassium levels which could be harmful for you. To prevent this rise in potassium levels, the combination of Eplerenone with hydrochlorothiazide may have been prescribed.

Q. Is there anything I need to be careful about if I am taking aspirin and have now started Eplerenone?

Aspirin may interfere with the working of Eplerenone due to which your blood pressure may not get adequately controlled. Aspirin and Eplerenone may increase the chances of rise in potassium levels in patients with kidney problems. Therefore, if both are to be used together, keep monitoring your blood pressure and potassium levels.


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