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Domperidone + Lansoprazole

Written By Dr. Syeda AafiaReviewed By Dr. Rajeev Sharma
Last updated 25 Nov 2025 | 09:37 AM (UTC)

Domperidone + Lansoprazole Uses

Domperidone+Lansoprazole is used in the treatment of gastroesophageal reflux disease (acid reflux) and peptic ulcer disease.

How Domperidone + Lansoprazole works

Domperidone + Lansoprazole is a combination of two medicines: Domperidone and Lansoprazole. Domperidone is a prokinetic which works on the upper digestive tract to increase the movement of the stomach and intestines, allowing the food to move more easily through the stomach. Lansoprazole is a proton pump inhibitor (PPI) which works by reducing the amount of acid in the stomach which helps in the relief of acid-related indigestion and heartburn.

Common side effects of Domperidone + Lansoprazole

Diarrhea, Headache, Flatulence, Nausea, Vomiting, Constipation, Abdominal pain, Fundic gland polyps
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Expert advice for Domperidone + Lansoprazole

  • You have been prescribed Domperidone + Lansoprazole for the treatment of acidity and heartburn.
  • Take it one hour before the meal, preferably in the morning.
  • It is a well-tolerated medicine and provides relief for a long time.
  • Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away.
  • Inform your doctor if you do not feel better after taking it for 14 days as you may be suffering from some other problem that needs attention.
  • Long-term use can cause weak bones and deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.