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Dipyridamole

INFORMATION

Uses

Dipyridamole is used to prevent pulmonary embolus (blood clot in lungs) and blood clot formation after cardiac valve replacement.

How it works

Dipyridamole prevents platelets from sticking together which decreases the formation of harmful blood clots.

Common side effects

Diarrhoea, Increase in temperature, Face redness, Headache

AVAILABLE MEDICINE

Expert advice

  • Do not use dipyridamole tablet, if you are allergic to dipyridamole or any other ingredients.
  • Do consult your doctor before taking dipyridamole, if you have disorders of blood vessels in the heart (coronary artery disease); narrowing/blocking of valves in the heart (aortic stenosis); low blood pressure (hypotension); chest pain (angina) or heart attack (myocardial infarction).
  • Do not use dipyridamole, if you have myasthenia gravis (neuromuscular disease characterized by weak muscles and unusual tiredness).
  • Use of dipyridamole is not recommended in children aged below 12 years.
  • You may experience pulsating headaches while taking dipyridamole which usually disappears when dose is reduced.
  • Do consult your doctor before taking dipyridamole, if you are pregnant (especially in the first trimester), planning to become pregnant or breastfeeding.

Frequently asked questions

Dipyridamole

Q.Is dipyridamole a blood thinner/anticoagulant?
Yes. Dipyridamole is a blood thinner or anticoagulant and reduces risk of blood clots by inhibiting platelet activity that is essential in clot formation

Q.Is dipyridamole a prodrug?
No. Dipyridamole is an active form of the drug

Q.Is dipyridamole a statin/NSAID?
No. Dipyridamole is a blood thinner or anticoagulant and reduces risk of blood clots. It does not have effects like statins (lowering blood cholesterol) or non-steroidal anti-inflammatory drugs NSAIDs (reducing pain and inflammation)

Q.What is dipyridamole used for/prescribed for/what does it treat/what are dipyridamole tablets for?
Dipyridamole is used along with other drugs (e.g. aspirin) to reduce risk of blood clots (deep venous thrombosis, recurrent venous thrombosis) which may occur typically after surgeries (e.g. heart valve replacement surgery)

Q.Does dipyridamole contain aspirin?
Dipyridamole and aspirin are two different drugs with similar uses but different mechanism of action. Some marketed medicines may contain a combination of aspirin and dipyridamole (e.g. Aggrenox)

Q.How does dipyridamole work?
Dipyridamole belongs to a class of drugs called antithrombotic (anticoagulant) drugs with antiplatelet activity. It reduces clot formation by interfering with the activation of platelets which is essential in clot formation

Q.How does dipyridamole stress test work?
The dipyridamole stress test or thallium scan test helps your doctor identify areas of your heart which do not receive enough blood supply (myocardial perfusion) due to diseases of blood vessels in the heart (coronary artery disease). Dipyridamole is directly administered into blood vessels (IV) to induce stress on the heart which is similar to physical exercise by increasing blood flow to the heart. It is usually used in patients who cannot exercise.


Content on this page was last updated on 24 November, 2016, by Dr. Varun Gupta (MD Pharmacology)