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Desloratadine is used to relieve symptoms such as sneezing, runny nose, red, itchy and tearing eyes and rash caused due to allergy.

How it works

Desloratadine belongs to the class of medicines called antihistamines. It works by blocking the action of histamine, a chemical substance in the body that causes allergic symptoms.

Common side effects

Diarrhoea, Abdominal pain, Dizziness, Dry mouth, Pain during periods, Fatigue, Headache, Insomnia, Loss of appetite, Muscle pain, Sore throat, Stomach upset


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Expert advice

  • Desloratadine may be taken with or without food
  • Tell your doctor if you are or planning to become pregnant or are breastfeeding.
  • Do not drive or operate machinery during desloratadine therapy as it may cause dizziness.
  • Do not give to patients allergic to desloratadine, loratadine or any of its ingredients.
  • Do not give to Children less than 2 years.

Frequently asked questions


 Q. Is desloratadine the same as loratadine/ Is desloratadine better than loratadine?
Desloratadine is the major metabolite of loratadine and the two drugs are similar in safety and effectiveness.
Q. Is desloratadine a steroid/ decongestant/ an antihistamine?
Desloratadine belongs to class of drugs called antihistamines. It is not a decongestant or a steroid.
Q. Is desloratadine over the counter?
Desloratadine is not an over the counter medicine. It is sold only upon a prescription by a registered medical practitioner.
Q. Does desloratadine cause drowsiness/ weight gain/ high blood pressure/ raise blood pressure?
Desloratadine is not known to cause drowsiness/ weight gain/ high blood pressure/ raise blood pressure. However, consult your doctor if you experience such side effects.

Content on this page was last updated on 30 September, 2016, by Dr. Varun Gupta (MD Pharmacology)