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Cisapride is used in adults in the treatment of night-time heartburn that occurs when stomach contents reflux in to the food pipe (gastro esophageal reflux disease [GERD]).

How it works

Cisapride is a prokinetic drug which promotes forward flow of stomach contents including stomach acid and prevents their reflux into the food pipe thereby preventing heartburn.

Common side effects

Chest pain, Cough, Headache, Nasal congestion, Stomach discomfort, Stomach upset, Vision changes, Constipation, Diarrhoea


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Expert advice

  • Do not take cisapride if you have history of irregular heartbeats, heart disease, kidney disease or lung disease.
  • Stop taking cisapride and contact your doctor immediately if you faint, become dizzy or develop any other unusual symptoms.
  • Tell your doctor if you are pregnant or planning to become pregnant or breastfeeding.
  • Never take more than the recommended dose of cisapride as it can adversely affect normal heartbeat of an individual.
  • Do not drink alcohol or take medicines called benzodiazepines along with cisapride as they can cause excessive drowsiness.

Frequently asked questions


Q. How long does it take cisapride to act?
It takes approximately 15-30 minutes for cisapride to act.
Q. Is cisapride banned?
Yes, cisapride is banned in India and many other countries around the globe.
Q. Does Nexium contain cisapride?
No. Nexium is brand (proprietary) name for esomeprazole, a proton pump inhibitor drug used to prevent excessive stomach acid secretion, which further prevents reflux.

Content on this page was last updated on 30 September, 2016, by Dr. Varun Gupta (MD Pharmacology)