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Cefpodoxime is a cephalosporin antiboitic with similar structure as that of penicillin. It is used in the treatment of certain  bacterial infections in the body like urinary tract infection, sexually transmitted disease (gonorrhea), lung infection (pneumonia), kidney infection (pyelonephritis), sinusitis, skin or soft tissue Infection, inflammation of tonsils (tonsillitis), sore throat (pharyngitis), and upper respiratory tract infection.

How it works

It works by interfering with the formation of the outer covering (cell wall) of bacteria so that the wall ruptures and results in the death of the bacteria.

Common side effects

Diarrhoea, Skin rash, Stomach upset, Vomiting


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Expert advice

Do not take cefpodoxime within 2 hours of antacids or H2 antagonists (ranitidine, famotidine).Take this medicine with meals or a snack for better absorptionMake sure you finish the entire course of treatmentConsult your doctor:
  • If you are allergic to cefpodoxime or any other cephalosporin antibiotic such as cefadroxil, cephalexin, penicillin, or any other drugs.
  • If you have diarrhea, inflammation of large intestine (colon) colitis, or stomach problems, blood clotting problem.
  • If you have or had kidney or liver disease.
  • If you are having surgery, including dental surgery, tell the doctor or dentist that you are taking cefpodoxime.
  • If you have taken cefpodoxime repeatedly or for longer duration.

Frequently asked questions


Q. Is cefpodoxime a sulfa drug/steroid/penicillin?
No, cefpodoxime belongs to class of medication called as cephalosporin antibiotics.
Q. Is Cefpodoxime/ cefodem xp 325/ cefodem 200/ monocef-o/ kefpod safe?
Cefpodoxime (also available as cefodem xp 325/cefodem 200/ monocef-o/kefpod) is safe at the prescribed dose by the doctor. Patients should follow the advice of the doctor regarding its use.
Q. What are cefpodoxime/ cefodem xp 325/ cefodem 200/ monocef-o/ kefpod/ gudcef 200/ gudcef?
Cefpodoxime belongs to class of medication called as cephalosporin antibiotics. It is used for the treatment of infections caused by bacteria.
Q. Is cefpodoxime a sulfa drug/ penicillin/ steroid/ an antibiotic?
Cefpodoxime is an antibiotic belong to class of medication called as cephalosporin. It is not a steroid and does not contain penicillin or sulpha.

Content on this page was last updated on 28 September, 2016, by Dr. Varun Gupta (MD Pharmacology)