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Cefpirome is used to treat lower respiratory tract infections, complicated upper and lower urinary tract infections, bacteremia/septicemia (bacteria in the blood), skin and soft tissue infections, severe infections in intensive care patients, and infections in neutropenic (patients who have low white blood cells) and immunocompromised (impaired immune system) patients.

How it works

Cefpirome belongs to class of medications called cephalosporin antibiotics. It works by arresting the bacterial cell wall synthesis resulting in bacterial cell death.

Common side effects

Vomiting, Nausea, Abdominal pain, Abnormal kidney function test, Abnormal liver function tests, Diarrhoea, Altered taste, Fever, Headache, Injection site irritation, Injection site pain, Itching, Reduced blood platelets, Allergic reaction


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Expert advice

  • Discontinue the use of cefpirome if you develop severe allergic reactions.
  • Inform your doctor if you are taking penicillins, as taking cephalosporins with penicillins may cause allergic reactions.
  • You may be monitored with renal function tests during treatment with combinations of cefpirome and furosemide or ethacrynic acid type and aminoglycosides antibiotics.
  • Take precautions while using cefpirome for longer duration (>10 days) along with beta-lactam antibiotics as you may develop granulocytopenia and, more rarely, agranulocytosis. You may be monitored with regular blood test.
  • Do not take live bacterial vaccines (BCG, typhoid) while on cefpirome therapy.
  • You must be aware that severe and persistent diarrhea may occur with cefpriome during treatment or in the weeks following discontinuation.

Content on this page was last updated on 30 September, 2016, by Dr. Varun Gupta (MD Pharmacology)