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Cefoperazone is used in the treatment of bacterial infections

How it works

Cefoperazone is an antibiotic. It kills the bacteria by attacking their cell wall. Specifically, it prevents the synthesis of a substance in the cell wall called peptidoglycan, which provides the cell wall with the strength required for survival of bacteria in human body.

Common side effects

Allergic reaction, Nausea, Diarrhoea

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Expert advice

Cefoperazone is usually given by a doctor or a nurse as an injection directly into the vein or muscle. Tell your doctor if you are taking cefoperazone and undergoing any blood or urine test, as it may affect the result. Do not start or continue the cefoperazone and consult your doctor:
  • If you have history of allergy due to cefoperazone or any other cephalosporin or penicillin antibiotics.
  • If you experience severe and persistent diarrhea after taking antibiotics.
  • If you are already taking any other antibiotic like aminoglycosides or other cephalosporins as it may cause kidney toxicity.

Frequently asked questions



What is cefoperazone sulbactam?
Combination of cefoperazone and sulbactam (beta lactamase inhibitor) are used for the treatment of intra-abdominal infections


Is cefoperazone nephrotoxic?
No, cefoperazona is not a nephrotoxic drug when given alone, but when given along with aminoglycosides (gentamicin, tobramycin) or other cephalosporins antibiotics, it may increase nephrotoxicity. Please consult your doctor before taking the drug


Is cefoperazone safe?
Cefoperazone is safe if used at prescribed doses for the prescribed duration as advised by your doctor.

Content on this page was last updated on 07 April, 2017, by Dr. Varun Gupta (MD Pharmacology)