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Cefazolin

INFORMATION

Uses

Cefazolin is used in the treatment of bacterial infections.

How it works

Cefazolin is an antibiotic. It kills the bacteria by attacking their cell wall. Specifically, it prevents the synthesis of a substance in the cell wall called peptidoglycan, which provides the cell wall with the strength required for survival of bacteria in human body.

Common side effects

Vomiting, Nausea, Confusion, Fatigue, Weakness, Flatulence, Generalized itching, Dizziness, Headache, Heartburn, Injection site swelling, Loss of appetite, Limb pain, Skin redness, White spots in the mouth, White patches on the tongue, White spots in the throat

AVAILABLE MEDICINE

Expert advice

  • Do not start or continue cefazolin and consult your doctor if you have severe allergic reaction, inflammation of large intestine (colitis), blood clotting problem, liver or kidney disease.
  • Caution should be taken when giving cefazolin to the children younger than 1 month old or to patients with diabetes as it may affect the results for urine glucose tests.
  • Tell your doctor if you are or planning to become pregnant or are breastfeeding.

Frequently asked questions

Cefazolin

Q.Is cefazolin safe?
Cefazolin is relatively safe if used at prescribed doses for the prescribed duration as advised by your doctor

Q.Is cefazolin a sulfa, penicillin, cephalosporin, or beta lactam drug?
Cefazolin does not contain sulfa and is not a penicillin drug. It is a beta lactam cephalosporin antibiotic

Q.Is cefazolin Keflex?
No, Keflex is a brand name for cephalexin

Q.Is cefazolin compatible with lactated ringer's, normal saline, Nacl, or potassium?
Cefazolin is compatible with normal saline, NaCl or potassium solution. It is not commonly used with lactated ringer's

Q.Can I take Ancef with a penicillin or sulfa allergy?
Ancef (brand name for cefazolin injection) cannot be given with a penicillin allergy. Precaution should be taken even when there is history of sulfa drugs

Q.Does cefazolin cover enterococcus, pseudomonas, or methicillin-resistant Staphylococcus aureus (MRSA)?
Cefazolin is effective against some strains of enterococcus bacteria but not effective against pseudomonas or MRSA

Q.Is cefazolin a vesicant?
No, cefazolin is not a vesicant (irritant) drug

Q.Does cefazolin need to be refrigerated?
Cefazolin needs to be stored at 20° to 25°C. It should not be frozen.


Content on this page was last updated on 24 November, 2016, by Dr. Varun Gupta (MD Pharmacology)