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Capsaicin Based Rubefacients



Treat minor aches and pains of the muscles/joints (e.g., arthritis, backache, sprains), nerve pain.

How it works

Capsaicin binds to a receptor called the vanilloid receptor subtype 1 (VR1). VR1, which can also be stimulated with heat and physical abrasion, permits cations to pass through the cell membrane and into the cell when activated. The resulting depolarization of the neuron stimulates it to signal the brain.

Common side effects

Rash, Application site burning, Dizziness, Shortness of breath, Swelling, Itching, Stinging sensation, Warm sensation


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Capsaicin Based Rubefacients

Content on this page was last updated on 28 September, 2016, by Dr. Varun Gupta (MD Pharmacology)