Information about Alteplase

Alteplase Uses

Alteplase is used in the treatment of heart attack and ischemic stroke.

How Alteplase works

Alteplase is a thrombolytic medication. It works by dissolving the harmful blood clots in the blood vessels. This restores the blood flow to the affected tissue, thereby preventing tissue death and improving outcomes.

Common side effects of Alteplase


Severe side effects of Alteplase

Orolingual angioedema, Cholesterol embolism, Re-embolization of deep vein thrombosis, Pulmonary embolism, Allergic reaction
Written By
MDS (Oral Pathology & Microbiology), BDS
Reviewed By
MD (Pharmacology), MBBS
Last updated
08 Sep 2022 | 06:39 AM (UTC)

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Available Medicine for Alteplase

ActilyseBoehringer Ingelheim
23899 to ₹498992 variant(s)

Expert advice for Alteplase

  • It should be given as soon as possible (within 12 hours) after the onset of a heart attack or within 4.5 hours of onset of stroke.
  • Let your doctor know immediately if you develop any nosebleeds, gum bleeding, black or tarry stools, or bruising. 
  • Do not discontinue the medicines started after this injection as it may increase your chances of having another heart attack or stroke.

Frequently asked questions for Alteplase


Q. How is Alteplase administered?

Alteplase should be administered under the supervision of a trained healthcare professional or a doctor only and should not be self-administered. The dose will depend on the condition you are being treated for and will be decided by your doctor. Follow your doctor’s instructions carefully to get maximum benefit from Alteplase.

Q. Is Alteplase safe?

Alteplase is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.

Q. Can the use of Alteplase increase the risk of bleeding?

Yes, Alteplase can increase the risk of bleeding. Always be careful while doing activities that may cause an injury or bleeding. Tell your doctor immediately if you notice any abnormal bruising or bleeding.

Q. What medicines should I avoid while taking Alteplase?

Alteplase can interact with several medicines. If you are already taking Alteplase, do not take any other medicine without talking to your doctor.

Q. When will I feel better after taking Alteplase?

Alteplase reduces your risk of developing blood clots in the blood vessels of your leg, lungs, heart and brain. You may not feel any difference after taking Alteplase. This does not mean that the medicine is not working, therefore keep taking this medicine as prescribed.


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