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Almotriptan is used to treat acute migraine attack in adults with a history of migraine with or without aura (warning signs before the pain begins).

How it works

Almotriptan belongs to a group of medicines called as selective serotonin receptor agonists. It works by narrowing the blood vessels around the brain and thereby stopping the pain signals to brain. It also reduces a chemical in the body that is responsible for generating migraine symptoms such as pain, nausea, sensitivity to light and sound, and thus provides relief during an attack.

Common side effects

Abdominal pain, Allergic reaction, Itching, Urticaria, Shortness of breath, Bloody diarrhea, Blue colour of skin, Fainting, Dizziness, Weakness, Dry mouth, Fatigue, Eye swelling, Lip swelling, Headache, Altered heart rate, Nausea, Sleepiness, Slow speech, Difficult speech, Facial swelling, Throat swelling, Numbness, Tingling sensation, Vomiting, Heaviness


Expert advice

  • Take almotriptan as soon as there is an onset of migraine headache.
  • Almotriptan is to be taken only if your condition has been confirmed as migraine by a doctor. 
  • Do not take almotriptan to treat other types of headaches.
  • Exercise caution while taking almotriptan if you smoke, have diabetes/high blood pressure/high cholesterol, are overweight or have a family history of heart disease, if you are a female who has had menopause /hysterectomy (surgery to remove uterus) or a male over 40 years of age, as you may be at a risk of developing heart disease.
  • Do not take almotriptan within 24 hours before or after using another migraine headache medicine (like other ‘triptan’ or ‘ergot’ medicines).
  • Do not take almotriptan when on medicines to treat viral/bacterial/fungal infections, as it increases the chance of side effects.
  • Do inform your doctor if you are taking any medicine for treatment of depression, (like monoamino oxidase inhibitors, selective serotonin reuptake inhibitors, serotonin noradrenaline reuptake inhibitors) as these medicines interact with almotriptan and may cause serious drug reaction.
  • Tell your doctor if you are/are planning to become pregnant or are breastfeeding. 
  • As almotriptan causes drowsiness, do not drive or operate machinery.
  • Almotriptan is not recommended to be used in children and adolescent (under 18 years of age).

Frequently asked questions


Q. Is almotriptan a narcotic?
No. Almotriptan is not a narcotic.
Q. What is almotriptan malate?
Almotriptan malate is a salt form of almotriptan.
Q. Can I take paracetamol with almotriptan?
There is no known interaction between almotriptan and paracetamol. However, this does not confirm that it is safe to take these drugs together. Always follow doctor’s advice on use of these medicines together.
Q. How long does almotriptan take to work?
Almotriptan action starts soon after consuming the medicine, and reaches its peak level within 1 to 3 hours.

Content on this page was last updated on 03 October, 2016, by Dr. Varun Gupta (MD Pharmacology)