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    Information about Acenocoumarol/Nicoumalone

    Acenocoumarol/nicoumalone uses

    Acenocoumarol/Nicoumalone is used for deep vein thrombosis, pulmonary embolism and stroke prevention. It prevents the formation of blood clots in the legs, lungs, brain or heart.

    How acenocoumarol/nicoumalone works

    Acenocoumarol/Nicoumalone is an oral anticoagulant. It acts by preventing the formation of harmful blood clots. Although it does not dissolve the existing blood clots, it inhibits them from growing larger and causing serious problems.

    Common side effects of acenocoumarol/nicoumalone

    Content Details
    Written By
    Dr. Anuj Saini
    Reviewed By
    Dr. Shilpa Garcha
    MD (Pharmacology), MBBS
    Last updated on:
    27 Dec 2019 | 01:08 PM (IST)
    Want to know more?
    Read Our Editorial Policy

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    Expert advice for Acenocoumarol/Nicoumalone

    • Avoid making sudden major changes to your diet during treatment with this medicine.
    • Acenocoumarol/Nicoumalone increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, using sharp objects or engaging in contact sports (e.g. football, wrestling).
    • Notify your doctor if you see blood in your vomit, urine or stool (black, tarry stools or bright red blood).
    • Do not consume alcohol while taking Acenocoumarol/Nicoumalone as this may increase its side effects.
    • If you are going to have a surgery or dental treatment, you may be asked to stop taking Acenocoumarol/Nicoumalone temporarily.
    • Do not discontinue use without consulting your doctor as this may increase your chances of having another heart attack or stroke.

    Frequently asked questions for Acenocoumarol/Nicoumalone


    Q. How long do I need to take Acenocoumarol/Nicoumalone?

    You should continue taking Acenocoumarol/Nicoumalone for as long as recommended by your doctor. Depending upon the condition you are being treated for, you may have to take it for several months or years or maybe for the rest of your life.

    Q. What should I avoid while taking Acenocoumarol/Nicoumalone?

    You should avoid alcohol while taking Acenocoumarol/Nicoumalone as alcohol may interfere with working of Acenocoumarol/Nicoumalone. In addition to that, avoid cranberry juice or other cranberry products as there may be a risk of enhanced blood thinning. Avoid breastfeeding or getting pregnant as it may harm your child.

    Q. Do I need to stop Acenocoumarol/Nicoumalone if I have to undergo a surgery?

    Depending on the type of surgery that is to be performed, your doctor will tell you whether to continue or stop Acenocoumarol/Nicoumalone. It will be decided by your doctor after weighing the risks and benefits of discontinuing Acenocoumarol/Nicoumalone.

    Q. Is Acenocoumarol/Nicoumalone same as warfarin?

    Both Acenocoumarol/Nicoumalone and warfarin are blood thinners, but they have some differences. Warfarin has a more stable blood thinning effect.

    Q. How long does it take for Acenocoumarol/Nicoumalone to start working?

    It takes a little longer for Acenocoumarol/Nicoumalone to start working. On an average, it may take 3-4 days for Acenocoumarol/Nicoumalone to show its blood-thinning effect. For these 3-4 days, heparin may be used and then discontinued.

    Q. What if I forget to take a dose?

    If you forget to take a dose of Acenocoumarol/Nicoumalone, take it as soon as you remember. However, if it is time for your next dose then skip the missed dose. Do not double the dose and continue your normal schedule. Keep a diary or set a reminder, so that you do not forget it often.

    Q. What monitoring is required while taking Acenocoumarol/Nicoumalone?

    The bleeding times should be carefully monitored from 2nd or 3rd dose of Acenocoumarol/Nicoumalone and till the clotting status is stabilized. Thereafter, the bleeding time can be monitored monthly. This frequency may be more in elderly.

    Content on this page was last updated on 27 December, 2019, by Dr. Varun Gupta (MD Pharmacology)