Cranberry
Cranberry
Cranberry is a tiny red-colored, shiny fruit that is sweet and sour in taste. It is rich in nutrients and has powerful antioxidant activity due to which it has recently gaining importance in the medical field. It can be consumed fresh or in the form of juice, jams, chocolates, sauces and candies.
Daily consumption of Cranberry juice or capsules is best known for the treatment and prevention of urinary tract infections (UTIs) as it inhibits the growth of infection-causing bacteria. Cranberry might also help to manage kidney stones due to its diuretic property. It prevents the deposition of calcium oxalate crystals that are responsible for kidney stone formation. Intake of Cranberry with honey is a well-known remedy to manage common cold symptoms.
Applying Cranberry in the form of a face pack also helps protect the skin from the harmful effects of free radicals due to its antioxidant and anti-aging properties.
Avoid excess consumption of Cranberry and Cranberry juice as it might upset your stomach[1][2][16].
Daily consumption of Cranberry juice or capsules is best known for the treatment and prevention of urinary tract infections (UTIs) as it inhibits the growth of infection-causing bacteria. Cranberry might also help to manage kidney stones due to its diuretic property. It prevents the deposition of calcium oxalate crystals that are responsible for kidney stone formation. Intake of Cranberry with honey is a well-known remedy to manage common cold symptoms.
Applying Cranberry in the form of a face pack also helps protect the skin from the harmful effects of free radicals due to its antioxidant and anti-aging properties.
Avoid excess consumption of Cranberry and Cranberry juice as it might upset your stomach[1][2][16].
What are the synonyms of Cranberry?
Vaccinium macrocarpon, Indian Cranberry, American Cranberry, large Cranberry[2]
What is the source of Cranberry?
Plant Based
Benefits of Cranberry

Modern Science View
Cranberry is beneficial in preventing urinary tract infections (UTIs). Cranberry does not allow the bacteria to adhere to the surface of the urinary tract. Thus, Cranberry inhibits the growth and colonization of the bacteria in the urinary tract[3][10].

Ayurvedic View
Urinary tract infection is described under the broad term of Mutrakcchra in Ayurveda. Mutra means ooze, krichra means painful. Thus, dysuria and painful urination are called as Mutrakcchra. In urinary tract infection, Cranberry juice helps to control burning sensation because it has Mutral (diuretic) effect. It increases the urine flow and subsides the symptoms of UTI like burning sensation during urination.
Tips:
1. Take 2-3 teaspoon Cranberry juice.
2. Mix with one glass of water.
3. Have it before food once or twice a day to get rid of UTI symptoms.
Tips:
1. Take 2-3 teaspoon Cranberry juice.
2. Mix with one glass of water.
3. Have it before food once or twice a day to get rid of UTI symptoms.

Ayurvedic View
Cranberry is good for managing cough and cold. Cough is commonly known as Kapha disorder and is caused by the accumulation of mucus in the respiratory tract. Cranberry helps to remove accumulated mucus due to its Ushna (hot) balancing property.
Tips:
1. Take ¼-½ teaspoon Cranberry powder.
2. Mix with water or honey.
3. Have it after lunch and dinner to get rid of common cold.
Tips:
1. Take ¼-½ teaspoon Cranberry powder.
2. Mix with water or honey.
3. Have it after lunch and dinner to get rid of common cold.

Modern Science View
Cranberry might be beneficial in managing coronary artery disease. Cranberry has antioxidant and anti-inflammatory properties. Cranberry protects the blood vessels and increases the level of nitric oxide. Nitric oxide in return dilates the blood vessels and improves the flow of blood. Cranberry also reduces arterial stiffness in patients with coronary artery disease[3][10].

Modern Science View
Cranberry might be beneficial in managing stomach ulcers caused by Helicobacter pylori (H pylori) infection. Cranberry has antibacterial and anti-inflammatory properties. It inhibits the growth of H. pylori in the stomach and prevents inflammation of the intestine[3][9].

Modern Science View
Cranberry might be beneficial in managing flu and associated symptoms. Cranberry also reduces inflammation associated with the bacterial infection[3][11].
How effective is Cranberry?
Likely effective
Urinary tract infections (UTIs)
Insufficient evidence
Common cold, Coronary artery disease, Helicobacter pylori (H.Pylori) infection, Influenza (flu)
Precautions when using Cranberry
Advice from Experts

Modern Science View
1. Cranberry may cause inflammation of the stomach lining in patients with gastritis. This is due to the increased absorption of vitamin B12[3].
2. Due to its acidic nature, Cranberry juice may counteract antacids.
3. Cranberry juice may also increase the effects of antibiotics in the urinary tract as well as increase the excretion of of some drugs in the urine.
2. Due to its acidic nature, Cranberry juice may counteract antacids.
3. Cranberry juice may also increase the effects of antibiotics in the urinary tract as well as increase the excretion of of some drugs in the urine.
Allergy

Modern Science View
People who are allergic to Vaccinium species such as blueberries may also be allergic to Cranberry. In such cases, consult your doctor before taking Cranberry[8].
Breastfeeding

Modern Science View
It is safe to take Cranberry in food amounts. However, it is advised to consult your doctor before taking Cranberry supplements during breastfeeding. Also, some Cranberry tinctures may contain high levels of alcohol due to which it must be avoided[8].
Minor Medicine Interaction

Modern Science View
1. Cranberry may increase the effects and side effects of drugs metabolized in the liver.
2. Cranberry may interact with Alzheimer’s drugs, antivirals agents, antifungals, anthelmintics, anticancer agents, cholesterol-lowering drugs, diuretic and salicylates[8].
2. Cranberry may interact with Alzheimer’s drugs, antivirals agents, antifungals, anthelmintics, anticancer agents, cholesterol-lowering drugs, diuretic and salicylates[8].
Moderate Medicine Interaction

Modern Science View
Cranberry may increase the effects of anticoagulant/antiplatelet drugs. So it is generally advisable to consult your doctor before taking Cranberry along with anticoagulant/antiplatelet drugs[3].
Patients with diabetes
Important

Modern Science View
Cranberry may increase insulin sensitivity and reduce the level of blood glucose. So it is generally advised to monitor the blood glucose level regularly while taking Cranberry supplements along with anti-diabetic drugs[7].
Patients with kidney disease

Modern Science View
Cranberry may increase the amount of oxalates in the body. Oxalate accumulation may cause kidney stones. So patients who have a tendency for formation of kidney stones should avoid consuming excessive Cranberry or Cranberry supplements[3][6].
Pregnancy

Modern Science View
It is safe to take Cranberry in food amounts. However, it is advised to consult your doctor before taking Cranberry supplements during pregnancy. Also, some Cranberry tinctures may contain high levels of alcohol due to which it must be avoided[8].
Side Effects

Modern Science View
Stomach upset/Diarrhoea
Recommended Dosage of Cranberry
- Cranberry Tablet - 1-2 tablets twice a day.
- Cranberry Capsule - 1-2 capsules twice a day.
- Cranberry Powder - ¼-1/2 teaspoon twice a day.
- Cranberry Juice - 2-3 teaspoon twice a day.
How to use Cranberry
1. Cranberry Tablets
a. Take 1-2 tablets of Cranberry with water after meals.
b. Follow this twice a day.
2. Capsules
a. Take 1-2 capsules of Cranberry with water after meals.
b. Follow this twice a day.
3. Cranberry Powder
a. Take ¼-½ teaspoon Cranberry Powder.
b. Mix with water or honey.
c. Have it after lunch and dinner.
4. Cranberry Syrup
a. Take 1 ½ cup fresh or frozen Cranberry.
b. Transfer in a saucepan.
c. Add 1 cup water to it.
d. Add ¾ cup of granulated sugar.
e. Bring the mixture to boil on medium heat.
f. Reduce the heat to low and let it simmer of about 15 minutes.
g. Once the Cranberries have fallen apart, take the saucepan off the fire.
h. Strain the mixture in a bowl and let it sit for about 1 hour till cool.
i. Discard the solid component and store the syrup in an airtight bottle in the refrigerator.
j. The syrup can be stored for upto 2 weeks.
5. Cranberry Juice
a. Take 2-3 teaspoon Cranberry Juice.
b. Mix with one glass of water.
c. Have it before taking food once or twice a day.
6. Cranberry Tea
a. Add 2-3 teaspoons of Cranberry powder in a saucepan.
b. Add 1 cup water to it
c. Add a cinnamon stick and 1-2 cloves.
d. Let the mixture come to a boil on medium heat.
e. Reduce the heat to low and simmer for 30 minutes.
f. Strain the tea and drink hot.
a. Take 1-2 tablets of Cranberry with water after meals.
b. Follow this twice a day.
2. Capsules
a. Take 1-2 capsules of Cranberry with water after meals.
b. Follow this twice a day.
3. Cranberry Powder
a. Take ¼-½ teaspoon Cranberry Powder.
b. Mix with water or honey.
c. Have it after lunch and dinner.
4. Cranberry Syrup
a. Take 1 ½ cup fresh or frozen Cranberry.
b. Transfer in a saucepan.
c. Add 1 cup water to it.
d. Add ¾ cup of granulated sugar.
e. Bring the mixture to boil on medium heat.
f. Reduce the heat to low and let it simmer of about 15 minutes.
g. Once the Cranberries have fallen apart, take the saucepan off the fire.
h. Strain the mixture in a bowl and let it sit for about 1 hour till cool.
i. Discard the solid component and store the syrup in an airtight bottle in the refrigerator.
j. The syrup can be stored for upto 2 weeks.
5. Cranberry Juice
a. Take 2-3 teaspoon Cranberry Juice.
b. Mix with one glass of water.
c. Have it before taking food once or twice a day.
6. Cranberry Tea
a. Add 2-3 teaspoons of Cranberry powder in a saucepan.
b. Add 1 cup water to it
c. Add a cinnamon stick and 1-2 cloves.
d. Let the mixture come to a boil on medium heat.
e. Reduce the heat to low and simmer for 30 minutes.
f. Strain the tea and drink hot.
Frequently asked questions

Modern Science View
Yes, Cranberry has very low calorie content but is rich in antioxidants, fibres and other essential phytochemicals. All the nutrients and goodness of Cranberry can be best obtained when eaten raw. It can also be consumed in the form of juice or along with cereal.

Modern Science View
Fresh Cranberry are harvested in the autumn season and are available in store from October through December. However, frozen or canned Cranberry are available throughout the year.

Modern Science View
Cranberry has very small seeds in the centre of the fruit. Although the seeds are edible, it is advisable not to consume excessive amounts of seeds.

Modern Science View
Dried Cranberry contains the same nutrients as fresh Cranberry. However, the process of drying reduces the vitamin content considerably. Also, if sugar is added to dried Cranberry, it may reduce the amount of good nutrients.
References
- Khaneja M , Gupta S, Sharma A.Pharmacognostical and Preliminary Phytochemical Investigations on fruit of Vaccinium macrocarpon aiton.Pharmacogn J.2015;7(6):333-338.
- WHO monographs on selected medicinal plants.Fructus Macrocarponii. Volume 4.149-166.
- WebMD.Cranberry: Uses, Side effects, Doses, Interactions [Internet].Atlanta [last updated in 2016].
- Feldman M, Barnett C.Relationships between the acidity and osmolality of popular beverages and reported postprandial heartburn.Gastroenterology.1995;108(1):125-131.
- Dugoua J-J, Seely D, Perri D et al.Safety and efficacy of Cranberry (Vaccinium macrocarpon) during pregnancy and lactation.Can J Clin Pharmacol.2008;15(1):e80-e86.
- Gettman MT, Ogan K, Brinkley LJ et al.Effect of Cranberry juice consumption on urinary stone risk factors.J Urol.2005;174(2):590-594.
- Shidfar F, Heydari I, Hajimiresmaiel SJ et al.The effects of Cranberry juice on serum glucose, apoB, apoA-I, Lp(a), and paraoxonase-1 activity in type 2 diabetic male patients.J Res Med Sci.2012;17(4):355-360.
- Ulbricht CE.Natural Standard:Herb and Supplement Guide, An Evidence Based Reference.Elsevier;2010.
- Zhao S, Liu H, Gu L. American cranberries and health benefits - an evolving story of 25 years. J Sci Food Agric.2018.
- Blumberg JB, Camesano TA, Cassidy A, et al. Cranberries and Their Bioactive Constituents in Human Health. American Society for Nutrition. Adv. Nutr.2013;4:618-632.
- Blumberg JB, Basu A, Krueger CG, et al. Impact of Cranberries on Gut Microbiota and Cardiometabolic Health: Proceedings of the Cranberry Health Research Conference 2015. American Society for Nutrition. Adv Nutr.2016;7:759S–70S.
- Leyner M, Goldberg B.Why Do Men Have Nipples?: Things You’d Only Ask a Doctor After Your Third Gin ‘n’ Tonic.Hachette UK.2015.
- Anhe FF, Roy D, Pilon G et al.A polyphenol-rich cranberry extract protects from diet-induced obesity, insulin resistance and intestinal inflammation in association with increased Akkermansia spp. population in the gut microbiota of mice.Gut. 2015 Jun;64(6):872-83.
- Al-Juhaishi AM, Mousa TH, Murtadha Al-Shehristani RM.Effect of Cranberry in Enhancing Oral Hypoglycemic Agents in Uncontrolled Type-II Diabetic Patients.Journal of Global Pharma Technology. 2018: 10(08):319-324.
- LEDDA A, BELCARO G, DUGALL M.Supplementation with high titer cranberry extract (Anthocran®) for the prevention of recurrent urinary tract infections in elderly men suffering from moderate prostatic hyperplasia: a pilot study.European Review for Medical and Pharmacological Sciences.2016: 20: 5205-5209.
Disclaimer
The content is purely informative and educational in nature and should not be construed as medical advice. Please use the content only in consultation with an appropriate certified medical or healthcare professional.