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Understanding the Test
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Content created by
Written by
Dr. Betina Chandolia
BDS, MDS - Oral Pathology and Microbiology
Reviewed by
Dr. Ashish Ranjan
MBBS, MD (Pharmacology)
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Plasminogen Activator Inhibitor-1

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This test is for
Male, Female
Test Preparation
  1. Do not eat or drink anything other than water for 8-12 hours before the test

Understanding Plasminogen Activator Inhibitor-1

What is Plasminogen Activator Inhibitor-1?

Plasminogen Activator Inhibitor-1 (PAI-1 ) test is done to diagnose a condition responsible for excessive and abnormal bleeding. This test helps to keep a check on PAI-1 protein responsible for blood clotting by inhibiting the plasminogen activators. PAI-1 deficiency disorder can result in unexplained mild-to-moderate delayed bleeding; while its excess can lead to venous and arterial thrombosis.

What is Plasminogen Activator Inhibitor-1 used for?

PAI-1 deficiency causes excessive bleeding due to any injury or physical trauma. If left undetected, the PAI-1 level may reduce even further and that can even prove to be fatal in the worst case.

Interpreting Plasminogen Activator Inhibitor-1 results


The normal PAI-1 range is 2-15 AU/mL.


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