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Tianeptine is used to treat mild, moderate or severe depression.

How it works

Tianeptine belongs to a class of medication called antidepressants. It increases the activity of brain by balancing the levels of certain chemical (serotonin).

Common side effects

Nausea, Palpitations, Liver enzyme increased, Drowsiness, Abdominal pain, Abnormal involuntary movements, Confusion, Constipation, Dizziness, Dry mouth, Shortness of breath, Fatigue, Flatulence, Hallucination, Headache, Increased sodium level in blood, Insomnia, Itching, Loss of appetite, Lump in throat, Muscle rigidity, Muscle pain, Back pain, Rash, Skin redness, Stomach pain, Tremor, Urticaria, Vomiting, Nightmare


Expert advice

  • Do not take if you are allergic to tianeptine or any of the other ingredients.
  • Do not take tianeptine with other drugs for depression.
  • Avoid taking tianeptine if you ever had suicidal thoughts.
  • Do not take tianeptine during pregnancy or lactation.
  • Do not take tianeptine if you have a history of addiction to drugs or alcohol or any other medication.
  • Do not drive or operate machines after taking tianeptine as you may experience reduced alertness.

Frequently asked questions


Q. Is tianeptine safe/ an opiate?
Tianeptine is not an opiate. It belongs to class of medications called antidepressants. It is safe if used at prescribed doses for the prescribed duration as advised by your doctor.

. Is tianeptine approved by FDA?
Tianeptine is not approved by FDA.
Q. Is tianeptine addictive?
Tianeptine causing addiction is very rare. However, consult your doctor, if you develop addiction.

Content on this page was last updated on 18 October, 2016, by Dr. Varun Gupta (MD Pharmacology)