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Piperazine
INFORMATION ABOUT PIPERAZINE
Piperazine Uses
Piperazine is used in the treatment of worm infections, schistosoma infections, diarrhea, periodontitis, liver abscesses, intestinal amoebiasis, hepatic amoebiasis and filariasis.
How Piperazine works
Piperazine belongs to class of drugs called anthelmintic. It works by paralyzing the worms and making them to pass in the stool. It is effective against the intestinal nematodes roundworm (Ascaris lumbricoides), pinworm and threadworm (Enterobius vermicularis). Piperazine produces a neuromuscular block leads to muscle paralysis of the worms which are consequently dislodged and expelled in the faeces.
Common side effects of Piperazine
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common
Nausea, Headache, Vomiting, Dizziness, Abnormal liver function tests, Fever, Abdominal pain, Hair loss, Vertigo
CONTENT DETAILS
Written By
Dr. Nitika Makhija
MDS, BDS
Reviewed By
Dr. Lalit Kanodia
MBA, MD Pharmacology
Last updated
28 Mar 2025 | 05:38 AM (UTC)
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Expert advice for Piperazine
  • You have been prescribed Piperazine to treat a variety of parasitic worm infections.
  • It should be taken with food.
  • Do not crush, chew, or break the tablet. Swallow it whole with a full glass of water.
  • It can be harmful to an unborn baby. Do not take it during pregnancy. Use birth control measures to prevent pregnancy while taking Piperazine.
  • Your doctor may monitor your blood counts and liver function before you start taking this medicine and regularly throughout your treatment.
  • Avoid being near people who are sick or have infections. Inform your doctor if you develop signs of infection.
  • Do not skip doses and finish the prescribed course, even if you start to feel better. Stopping it early may increase your risk of further infection.
  • You have been prescribed Piperazine to treat a variety of parasitic worm infections.
  • It should be taken with food.
  • Do not crush, chew, or break the tablet. Swallow it whole with a full glass of water.
  • It can be harmful to an unborn baby. Do not take it during pregnancy. Use birth control measures to prevent pregnancy while taking Piperazine.
  • Your doctor may monitor your blood counts and liver function before you start taking this medicine and regularly throughout your treatment.
  • Avoid being near people who are sick or have infections. Inform your doctor if you develop signs of infection.
  • Do not skip doses and finish the prescribed course, even if you start to feel better. Stopping it early may increase your risk of further infection.
Frequently asked questions for Piperazine
Piperazine is available on prescription only
Yes, Piperazine may cause hallucinations especially in patients with kidney problems. Please consult your doctor if you experience such side effects.