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Methoxsalen Topical

INFORMATION

Uses

Methoxsalen Topical is used in the treatment of acne (pimples) and vitiligo (loss of skin colour in patches).

How it works

Methoxsalen belongs to the class of medications called as psoralens. It is a photoactive (light-sensitive drug that absorbs ultraviolet light and becomes activated) medication, which upon activation damages the DNA of actively dividing cells, thereby killing them, providing relief from various skin disorders.

Common side effects

New growth on the skin, Altered appearance of mole, Blisters on skin, Burns on the treated area from overexposure to uva or sunlight, Itching, Skin redness, Swelling, Blister

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Expert advice

  • Wear UVA-absorbing, wrap-around sunglasses and cover exposed skin or use a sunblock (SP 15 or higher) for the twenty-four (24) hour period following treatment with methoxsalen topical.
  • Use extra caution for at least 48 hours following each treatment. After each treatment, cover your skin for at least 8 hours by wearing protective clothing.
  • Do not increase the amount of methoxsalen topical if you are taking or spending extra time in the sunlight or under an ultraviolet lamp.
  • You may have to undergo an eye examination before starting the treatment and also once a year thereafter.
  • Tell your doctor if you are pregnant, planning to become pregnant or are breastfeeding. 
  • Do not use if you are allergic to methoxsalen or any of its ingredients.
  • Do not use by Children < 12 years.
  • Do not use if you have a history of a light-sensitive conditions (e.g., albinism, lupus, porphyria, xeroderma pigmentosum).
  • Do not use if you having aphakia (no lens in the eye).
  • Do not use if you have a history of melanoma or certain other types of skin cancer.

Frequently asked questions

Methoxsalen Topical

Q.What is methoxsalen topical used for?
Methoxsalen topical is used in addition to ultraviolet light (found in sunlight and some special lamps) for treatment of vitiligo (skin disease characterized by presence of white patches on different parts of the body), psoriasis (a skin condition associated with red, raised, itchy and scaly patches), and mycosis fungoides, a type of skin lymphoma.


Content on this page was last updated on 30 September, 2016, by Dr. Varun Gupta (MD Pharmacology)