The use of Alprazolam+Melatonin is considered to be harmful for patients with known allergy to alprazolam or melatonin. Its use should also be avoided in patients with myasthenia gravis, any breathing difficulties or chest diseases, liver diseases and sleep apnea.

Alprazolam+Melatonin contains alprazolam which can make you dependent on the medicine. Dependence can lead to withdrawal symptoms when you stop the treatment abruptly. This mainly happens if you have been taking high doses or have been using it for a very long time. Withdrawal symptoms can include a headache, muscle pain, anxiety, restlessness, confusion, mood changes, difficulty in sleeping, irritability, nausea, vomiting, stomach upset and many others.

Keep Alprazolam+Melatonin in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.