Aromasin 25mg tablet
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Written By
MMST, MBBS
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Reviewed By
MBBS, MD (Pharmacology)
Last updated:
28 May 2021 | 11:59 PM (IST)
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Aromasin 25mg tablet

Prescription Required
Manufacturer
SALT COMPOSITION
Storage
Store below 30°C


Introduction

Aromasin 25mg tablet helps treat breast cancer in those women who have gone through menopause (postmenopausal). It helps treat breast cancer in those women who have taken tamoxifen (an anti-cancer medicine) for 2 to 3 years or whose disease has progressed following the treatment with tamoxifen

Aromasin 25mg tablet is a type of medicine called an aromatase inhibitor. It works by preventing the action of the Aromasin enzyme. This enzyme helps in producing the estrogen hormone in postmenopausal women. Most breast cancers require estrogen to grow (estrogen receptor-positive cancers). Controlling the production of this hormone helps stop the breast cancer cells from growing.

Aromasin 25mg tablets are usually taken once daily, preferably after a meal and at the same time each day. The dose and duration of treatment depend on the condition and response to the treatment. In most cases, the treatment with Aromasin 25mg tablets may be suggested for 2 or 3 years. However, in some cases, the doctor may also recommend taking it for a longer time. Follow the doctor’s instructions and do not stop the medication unless advised otherwise.

This medicine’s most common side effects include hot flushes, increased sweating, insomnia, tiredness, joint pain, headache, increased appetite, and nausea. However, these symptoms may vary from person to person. If they persist or become worrisome, consult the doctor right away. Additionally, Aromasin 25mg tablets may also affect fertility. Talk to your doctor if you have concerns about this. Let the doctor know if you are pregnant, planning to get pregnant, or breastfeeding, as this medicine may cause harmful effects to the developing baby. Use effective contraception while on treatment with this medication.

Before starting treatment with Aromasin 25mg tablets, the doctor may take blood tests to check your vitamin D level or bone density. Let them know if you still have menstrual periods, or have a problem with the liver or kidney. The doctor should also know about all other medicines you are taking, as they may make this medicine less effective or change how it works. Do not take this medicine if you are allergic to any of the ingredients of this medicine.

Uses of Aromasin 25mg tablet

Benefits of Aromasin 25mg tablet

Aromasin 25mg tablets relieve the symptoms of breast cancer. These symptoms may include breast lumps, bloody discharge from the nipple, or changes in the shape or texture of the breast. It works by altering the production of those hormones in the body that are essential for the growth and spread of cancer, especially estrogen. The treatment helps to prolong survival and improve the overall quality of life. Follow your doctor’s advice and do not stop taking it even if you feel well.

Side effects of Aromasin 25mg tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you are worried about them.

Common side effects of Aromasin 25mg tablet

  • Hot flushes
  • Increased sweating
  • Insomnia
  • Tiredness
  • Joint pain
  • Headache
  • Increased appetite
  • Nausea

How to use Aromasin 25mg tablet

Take Aromasin 25mg tablets in the dose and duration advised by the doctor. Swallow it as a whole. Do not chew, crush, or break it. Take this medicine with food.

How does Aromasin 25mg tablet works

Aromasin 25mg tablet is an aromatase inhibitor. It works by lowering estrogen production (natural female hormone) in the body. Cancer cells require estrogen hormone to grow and spread. Halting or controlling the secretion of estrogen, in turn, blocks the growth of some breast cancer cells.

Safety advice

warnings
Alcohol
CONSULT YOUR DOCTOR
It is unknown whether it is safe to consume alcohol with Aromasin 25mg tablets. In general, drinking alcohol should be kept to a minimum or avoided completely. Consult with your doctor.
warnings
Pregnancy
UNSAFE
Aromasin 25mg tablets may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Females of reproductive potential should use effective contraception during treatment and for 1-month after the last dose. Consult your doctor if you are pregnant or suspect pregnancy.
warnings
Breast feeding
UNSAFE
Aromasin 25mg tablets are probably unsafe to use during breastfeeding. They might pass into breast milk and could therefore harm your baby. Avoid breastfeeding while taking this medicine and for 1-month after the last dose.
warnings
Driving
CAUTION
Aromasin 25mg tablets may cause drowsiness, sleepiness, weakness, and dizziness. Do not drive or operate machinery if these symptoms occur.
warnings
Kidney
SAFE IF PRESCRIBED
Aromasin 25mg tablets are safe to use in patients with kidney disease. No dose adjustment of Aromasin 25mg tablets is recommended.
warnings
Liver
SAFE IF PRESCRIBED
Aromasin 25mg tablets are safe to use in patients with liver disease. No dose adjustment of Aromasin 25mg tablets is recommended.

WHAT IF YOU FORGET TO TAKE Aromasin 25mg Tablet?

If you miss a dose of Aromasin 25mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Quick tips

  • Take a few moments to lie down or take a nap whenever you feel tired. Eat well and drink plenty of liquids.
  • If you experience nausea, take anti-nausea medications as prescribed by your doctor, and eat small frequent meals. Sucking on lozenges and chewing gums may also help.
  • If you experience hot flushes, try wearing light clothing, staying in a cool environment, and putting a cool cloth on your head to reduce symptoms. Consult your doctor if it worsens or becomes intolerable.
  • Your doctor may regularly check your vitamin D level and bone mineral density to detect the need for supplements.
  • Do not take other drugs containing estrogen, such as hormone replacement therapy (HRT), while you are on treatment with Aromasin tablets, as this may interfere with its effectiveness.
  • Have regular follow-ups with your doctor. Your doctor will address your concerns and do a thorough examination during these visits.

Fact Box

Chemical Class
Androgens derivative
Habit Forming
No
Therapeutic Class
Aromatase inhibitor
Action Class
Antineoplastic

FAQs

Q. How do Aromasin 25mg tablet affect my bones? How do I manage it?

Aromasin 25mg tablets can cause bone loss leading to osteoporosis (thinning of bones) as a serious side effect. It decreases the levels of female hormones, which may reduce the mineral content of the bones, causing a significant reduction in bone strength. These lead to an increased risk of bone fractures on long-term use, like hip, wrist, or spine fractures. Inform your doctor if you have osteoporosis or if you are taking corticosteroids (these can increase the risk of osteoporosis) before starting your therapy. Also, get blood tests done to assess your vitamin D levels if you are not sure. Take enough calcium and vitamin D to reduce the risk.

Q. Who should not take Aromasin 25mg tablet?

Aromasin 25mg tablets should be avoided by those allergic to exemestane, an active ingredient of Aromasin 25mg tablets, or any other ingredients. If you have not had your menopause (if you still have your regular monthly periods), are planning a baby, are pregnant, or are breastfeeding, you should refrain from taking Aromasin 25mg tablets.

Q. What should I tell my doctor before starting treatment with Aromasin 25mg tablet?

Before starting treatment with Aromasin tablet, tell your doctor if:
  • You are taking estrogen-containing medicines, including hormone replacement therapy or birth control pills.
  • You are taking any other over-the-counter medicines, herbal supplements, and vitamins as they can affect how Aromasin 25mg tablets work.
  • You are taking any other over-the-counter medicines, herbal supplements, and vitamins as they can affect how Aromasin 25mg tablets work.
  • You have low vitamin D levels, or if you are suffering from any bone-related issues like osteoporosis.
  • You are planning a baby, are pregnant, or breastfeeding.

Q. Are there any medicines that should be used with caution with Aromasin 25mg tablet?

Yes, certain medicines must be used with caution while taking Aromasin 25mg tablets. These include rifampicin (an antibiotic), carbamazepine, or phenytoin (anticonvulsants used to treat epilepsy) among others. Herbal medicines such as Hypericum perforatum or those containing it as an ingredient should also be used with caution.

Q. Can I stop taking Aromasin 25mg tablets if I feel well?

No, you must not stop taking Aromasin 25mg tablets even if you feel well. Continue taking it for the duration advised by the doctor.

Q. How do Aromasin 25mg tablet affect my liver?

Aromasin 25mg tablets may affect the functioning of your liver. Look for signs such as tiredness, yellowish discoloration of your skin or the white portion of your eyes, change in the urine color, nausea, vomiting, or decreased appetite. Additionally, you may develop pain on the right side of your stomach, have itching, or easy bruising too. In case you observe any of these, you should consult your doctor without any delay. Your doctor will monitor your liver by conducting liver function tests. You might need dose adjustments or stopping the treatment for some time till you recover.

Q. Do Aromasin 25mg tablets raise blood pressure?

Yes, Aromasin 25mg tablets may raise your blood pressure. Regular monitoring of blood pressure is recommended for all patients who are on treatment with Aromasin 25mg tablets. Make sure that the blood pressure is within the normal range. You may be prescribed medicines to control your blood pressure if it is on the higher side. If you are hypertensive, you must consult your doctor before starting treatment with this medicine.

Q. To keep my blood pressure under control, what other lifestyle changes should I make while taking Aromasin tablets?

Lifestyle changes are important in keeping you healthy if you are taking Aromasin tablets. You may consider the following changes:
  • Avoid taking excess salt in your diet and find ways to reduce or manage stress in your life.
  • Practice yoga or meditation or take up a hobby.
  • Ensure that you have a sound sleep every night.
  • Ensure that you have a sound sleep every night.
  • Exercise regularly and take a balanced diet that includes whole grains, fresh fruits, vegetables, and fat-free products. You may even get a diet chart made by a dietitian that suits your requirements.
Consult your doctor if you need any further guidance to get the maximum benefit of Aromasin tablets and keep yourself healthy.

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Disclaimer:

1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Aromasin (Exemestane tablet). New York, NY: Pfizer Inc.; 2018. [Accessed 17 Aug. 2021] (online) Available from: External Link
  2. Aromasin (Exemestane Tablets) [Brochure]. 2016. [Accessed 14 Aug. 2021] (online) Available from: External Link
  3. Aromasin (Exemestane). New York, New York: Pfizer Inc.; 2018. [Accessed 14 Aug. 2021] (online) Available from: External Link
  4. Aromasin (Exemestane Tablets). Pfizer Inc.; 2021. [Accessed 14 Aug. 2021] (online) Available from: External Link
  5. Exemestane. Ascoli Piceno, Italy: Pfizer Italia S.r.l.; 2018. [Accessed 14 Aug. 2021] (online) Available from: External Link
  6. Exemestane [Package Leaflet: Information for the User]. Middlesex, UK: Glenmark Pharmaceuticals Europe Ltd.; 2018. [Accessed 14 Aug. 2021] (online) Available from: External Link
  7. Breast Cancer Information and Support. Aromasin (Exemestane). [Last Updated 28 Mar.2020]. [Accessed 14 Aug. 2021] (online) Available from: External Link

Manufacturer/Marketer address

The Capital, 1802, 18th Floor , Plot No. C-70, ‘G’ Block , Bandra Kurla Complex, Bandra East , Mumbai – 400051.
Country of origin: United kingdom

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