BNP

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Overview
Interpreting Results
FAQ's

Overview of BNP

What is BNP?

The B-Type Natriuretic Peptide (BNP) is a substance produced by the left ventricle of the heart which helps to relax the blood vessels for smooth blood flow. The BNP Test measures the levels of the protein BNP in blood.




Why is BNP done?

The B-Type Natriuretic Peptide Test is performed:

·         To help in the detection, diagnosis, and evaluation of the severity of congestive heart failure (CHF)





What does BNP Measure?

The B-Type Natriuretic Peptide is a substance secreted by the left ventricle of the heart due to the stretching of the heart chamber during pumping of blood. It helps in the relaxation of blood vessels for smooth blood flow. The heart continuously secretes a precursor substance called pro-BNP which is converted to BNP to maintain a low constant level in blood. In case of a congestive heart failure, the heart works harder to pump blood causing extra pressure in the heart muscles. This leads to an increase in the production of BNP to help stimulate the blood vessels to relax and reduce the pressure on the heart. It may also occur in other conditions affecting the circulatory system like blockages in blood vessels.

The B-Type Natriuretic Peptide was initially named the Brain Type Natriuretic Peptide since it was first detected in the brain tissues. Later, it was renamed to B-Type to distinguish it from Atrial or A-Type Natriuretic Peptide (ANP), which is another substance with similar function also produced in the heart.



Preparation for BNP

  • No special preparation required

Sample Type for BNP

The sample type collected for BNP is: Blood

Interpreting BNP results

Interpretations

Normal range (Approx.): Below 29.40 pg/mL

Higher than normal levels of BNP indicates heart conditions including CHF. Levels are directly proportional to the severity of the condition.





Answers to Patient Concerns & Frequently Asked Questions (FAQs) about BNP

Frequently Asked Questions about BNP

Q. How is this test performed?
This test is performed on a blood sample. A syringe with a fine needle is used to withdraw blood from a blood vessel in your arm. The healthcare provider will tie an elastic band around your arm to make the blood vessels swell with blood. This makes it easier to withdraw blood. You may be asked to tightly clench your fist. Once the veins are clearly visible, the area is cleaned with an antiseptic solution and then the needle is inserted into the blood vessel to collect the sample. You will feel a tiny pinprick during the procedure. Blood sample once collected will then be sent to the laboratory.
Q. Is there any risk associated with this test?
There is no risk associated with the test. However, since this test involves a needle prick to withdraw the blood sample, in very rare cases, a patient may experience increased bleeding, hematoma formation (blood collection under the skin), bruising or infection at the site of needle prick.
Q. Is there any preparation required before the BNP test?
Inform the doctor about any medications you may be taking. No other preparations are required unless specified by your doctor.
Q. What other tests can be prescribed by your doctor in case the results of BNP Test is not normal?
Other tests that may be prescribed upon appearance of an abnormal result include: · ANP Test · Lipid Profile Test · Chest X-Ray · Electrocardiogram · Echocardiogram
Q. What conditions are associated with high BNP levels?
Conditions associated with high BNP levels include: · Heart failure · Asymptomatic left ventricular dysfunction · Arterial & pulmonary hypertension · Cardiac hypertrophy · Valvular heart disease · Arrhythmia · Acute coronary syndrome · Acute & chronic renal failure · Liver cirrhosis · Hyperaldosteronism · Cushing’s syndrome
Q. What are the common symptoms of heart failure?
The most common clinical symptoms that may indicate a heart failure are: · Difficulty breathing · Shortness of breath · Fatigue · Swelling (edema) in the feet, ankles, legs, abdomen
Q. What is congestive heart failure?
Congestive heart failure is a progressive condition where the heart muscles are unable to efficiently pump blood in sufficient quantities required for the rest of the body. Congestive heart failure can be caused by a number of factors, such as: · High blood pressure (Hypertension) · Coronary artery diseases, where cholesterol deposition occurs on the inner wall of the blood vessels, causing blockage in blood supply · Conditions affecting the heart valves, making them ineffective · Conditions not directly related to the heart, such as diabetes, obesity, severe infections, etc.
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About Oncquest Labs

With a decade of experience under its belt, Oncquest is known for its excellence in Clinical Diagnostics. From its first avatar as an R&D focused entity, Oncquest has evolved into a reference laboratory in the field of Oncology, and more recently into a multi-platform Pathology Services provider with a core focus in Molecular Pathology and Surgical Pathology Services. Its logistic capabilities and geographical spread makes Oncquest an ideal associate for clinical activities in India. Oncquest’s accredited quality systems ensure customer satisfaction through any of its customer-centric service offerings. Oncquest’s recent advances in the areas of Companion Diagnostics and Pharmacogenomics have also allowed for and encouraged greater penetration of Personalized Medicine into the Indian healthcare market, making it the future epicentre of the many technological advancements in healthcare, to come. Its close association with many Hospitals across India stands testament to the faith that Oncquest has instilled in the doctors and patients which avail of its services. Oncquest is fast becoming a cornerstone for a blooming healthcare industry. With over a decade of experience in the field of molecular diagnostics and pathology services, Oncquest Laboratories has earned its reputation of clinical excellence in the Indian market. Our advanced technologies and global quality systems have ensured that we stay ahead of the curve, and this has resulted in our association with some of the most advanced clinicians, hospitals and research organizations in the country. As India gets set for a clinical revolution, ushering in a trend of new healthcare services and products, Oncquest has defined its place as a partner of choice for those who bring value to our proud subcontinent. Our national reach and sizeable knowledge base allows us to be at the forefront of scientific advances, and an ideal partner for clinical activities. We strive to be connected with the best in the industry and we welcome partnership in ideas and technologies. For example, Oncquest’s early adoption and utilization of genetic sequencing technologies has resulted in many “first to market” assays, which have subsequently been adopted in several treatment and monitoring protocols. Innovation is an essential part of our DNA. We welcome challenges, and look forward to associating with you and your organizations to develop pioneering solutions and to tackle some of the most pressing issues faced in our world.

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