Test Detail
Interpreting Results

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Written by
Dr. Betina Chandolia
BDS, MDS - Oral Pathology and Microbiology
Reviewed by
Dr. Ashish Ranjan
MBBS, MD (Pharmacology)
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Terminal Deoxynucleotidyl Transferase

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This test is for
Male, Female
Test Preparation
  1. No special preparation required


What is TdT?

The Terminal Deoxynucleotidyl Transferase (TDT) test is performed to classify lymphomas and leukemias, to differentiate between lymphoblastic and non-lymphoblastic leukemia, to diagnose acute lymphoblastic leukemia, lymphoblastic lymphomas and lymphoid blast crisis of CML (Chronic Myelgenous Leukemia).

Why is TdT done?

The test is performed when a patient exhibits symptoms of leukemia such as-
>Joint pain
>Frequent infections
>Mouth ulcer
>Swollen lymph nodes
>Unexplained weight loss
>Loss of appetite

Interpreting TdT results


The results depend upon the stain used for the classification and distinction of leukemias and lymphomas. So, a positive result is indicated by the presence of positive staining of the ALL B-cells and negative staining, i.e., no staining in case of absence of TdT positive cells.


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