Location IconGPS icon
QUICK BUY! Get 25% off on medicines*
Zonisamide
INFORMATION ABOUT ZONISAMIDE
Zonisamide Uses
Zonisamide is used in the treatment of epilepsy/seizures and epilepsy.
How Zonisamide works
Zonisamide is an antiepileptic medication. It prevents seizures in patients with epilepsy by suppressing the abnormal and excessive activity of the nerve cells in the brain.
Common side effects of Zonisamide
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common
Dizziness, Drowsiness, Headache, Nausea, Decreased appetite, Abdominal pain, Weight loss
CONTENT DETAILS
Written By
Dr. Swati Mishra
BDS
Reviewed By
Dr. Rajeev Sharma
MBA, MBBS
Last updated
03 Dec 2024 | 05:16 AM (UTC)
We provide you with authentic, trustworthy and revelant information
Read our editorial policy
Expert advice for Zonisamide
  • Take your medication regularly as directed by your doctor as missing doses can trigger seizures.
  • Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
  • Some healthy tips to prevent seizures:
    • Take a healthy diet along with regular exercise.
    • Practice yoga every day.
    • Get enough sleep at nighttime.
    • Limit the use of screen time such as mobile/ laptop.
    • Take your medication on time.
  • Do not drive or do anything that requires mental focus until you know how this medicine affects you.
  • Drink plenty of water while taking Zonisamide to reduce the risk of kidney stones and heat stroke. Inform your doctor if you have sudden pain in your stomach, pain on urinating, or if you find blood in your urine.
  • It may cause loss of appetite and weight. Monitor your weight regularly.
  • Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
  • Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.
  • Zonisamide is used along with other medicines to help control your seizures.
  • Do not drive or do anything that requires mental focus until you know how this medicine affects you.
  • Dress lightly during hot climates or when exercising and check carefully for signs of decreased sweating or heat stroke.
  • Drink plenty of water while taking Zonisamide to reduce the risk of kidney stones and heat stroke. Inform your doctor if you have sudden pain in your stomach, pain on urinating, or if you find blood in your urine.
  • It may cause loss of appetite and weight. Monitor your weight regularly.
  • Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
  • Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.
  • Take your medication regularly as directed by your doctor as missing doses can trigger seizures.
  • Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
  • Some healthy tips to prevent seizures:
    • Take a healthy diet along with regular exercise.
    • Practice yoga every day.
    • Get enough sleep at nighttime.
    • Limit the use of screen time such as mobile/ laptop.
    • Take your medication on time.
Frequently asked questions for Zonisamide
Do not stop taking Zonisamide without talking to your doctor. Stopping Zonisamide suddenly may cause serious problems, including seizures that will not stop.
Severe muscle pain or weakness, with or without fever, could be due to Zonisamide. Consult your doctor immediately. The doctor may suggest some blood tests to check your levels of serum creatine phosphokinase and aldolase enzymes. Elevated levels of these enzymes may prompt the doctor to discontinue Zonisamide.
Zonisamide works well in children and is well tolerated by most of them. The common side effects in children include problems with thinking or behavior, followed by stomach upset. One dangerous side effect of Zonisamide in children is decreased sweating with fever. This affects children but not adults and is more common in summers.
Though uncommon, Zonisamide may increase the risk of suicidal thoughts or behavior. Sometimes, it can also be due to the disease itself. You should immediately consult your doctor who will consider discontinuing Zonisamide. We recommend that you take the help of your friend or relative to go to the hospital.
Yes, Zonisamide may cause weight loss. If you lose weight, consult a dietician for dietary supplement or try to increase your food portions. In case you lose a lot of weight, consider discontinuing Zonisamide after consulting your doctor. Weight loss may be more serious in children, so be cautious and keep monitoring the weight.
No, Zonisamide does not interfere with the working of birth control pills.
Yes, if you are at a risk of developing kidney stones, taking Zonisamide may increase that risk. Stones can lead to further kidney damage. The symptoms of kidney stones include severe sharp pain in lower abdomen or back pain. Increase your fluid intake which can reduce the risk of kidney stones. Consult your doctor if you get any such symptoms.