Vincristine+Mannitol is used in the treatment of cancer.
How Vincristine + Mannitol works
Vincristine + Mannitol is a combination of two medicines. Vincristine is an anticancer medicine. It works by inhibiting the duplication of genetic materials (DNA and RNA) that is required for cell growth and multiplication of the cancer cells. The addition of Mannitol allows Vincristine to enter the brain by opening the blood-brain barrier and act against the cancer cells.
Common side effects of Vincristine + Mannitol
Constipation, Nausea, Fever, Fatigue, Peripheral neuropathy (tingling and numbness of feet and hand), Febrile neutropenia, Diarrhea, Anemia (low number of red blood cells), Decreased appetite, Insomnia (difficulty in sleeping)
Vincristine + Mannitol is given to treat various types of cancer.
Decreased sensation, numbness, and tingling in fingers and toes may become progressively worse with repeated doses of Vincristine + Mannitol. It is important to report this to your doctor.
Your health care provider may prescribe a stool softener to help prevent constipation that may be caused by this medicine.
Drink plenty of water and follow a healthy diet.
You may be at risk of infection so try to avoid crowds or people with colds, and report fever or any other signs of infection immediately to your doctor.
To reduce nausea, take anti-nausea medications as prescribed by your doctor, and eat small, frequent meals.
Reviewed By Dr. Rajeev Sharma