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Venetoclax
INFORMATION ABOUT VENETOCLAX
Venetoclax Uses
Venetoclax is used in the treatment of sickle cell anemia, blood cancer (chronic lymphocytic leukemia), prostate cancer, blood cancer (acute lymphocytic leukemia), soft tissue sarcoma and Hodgkin’s disease.
How Venetoclax works
Venetoclax is an antineoplastic agent that is used to treat certain blood cancers. It works by blocking a protein called B-cell lymphoma/leukemia 2 (BCL-2), which helps cancer cells live longer than they should. It turns off this protein and helps the cancer cells die naturally and be removed from the body.
Common side effects of Venetoclax
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common
Decreased white blood cell count (neutrophils), Low blood platelets, Anemia (low number of red blood cells), Diarrhea, Nausea, Upper respiratory tract infection, Cough, Musculoskeletal (bone, muscle or joint) pain, Fatigue, Edema (swelling)
CONTENT DETAILS
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Written By
Dr. Anuj Saini
MMST, MBBS
Reviewed By
Dr. Sachin Gupta
MD Pharmacology, MBBS
Last updated
23 May 2025 | 07:19 PM (UTC)
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Medicine brands for Venetoclax
Expert advice for Venetoclax
- Regular blood tests are essential to monitor your blood cell counts and kidney function. This helps your doctor adjust your treatment if needed.
- Keep Venetoclax in its original packaging, away from moisture and heat. Do not transfer them to another container.
- Keep an updated list of all medicines, vitamins, and supplements you are taking, and share it with every doctor you visit.
- Venetoclax can lower your body’s ability to fight infections. Report signs like fever, chills, or persistent sore throat promptly to your doctor.
Frequently asked questions for Venetoclax
Take Venetoclax exactly as prescribed by your doctor. It is usually started at a low dose and increased gradually. Always follow your dosing schedule and avoid missing doses.
Yes. Avoid grapefruit or Seville oranges, as they can affect how Venetoclax works. Also, tell your doctor about all other medicines you are taking to avoid possible interactions.
No, do not stop or change your dose without talking to your doctor. Even if you feel better, it’s important to continue as prescribed to keep the cancer under control.
Venetoclax is not recommended during pregnancy or breastfeeding. Discuss with your doctor if you are pregnant, planning to become pregnant, or breastfeeding.