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    Rifampicin + Isoniazid + Ethambutol + Pyrazinamide + Vitamin B6 (Pyridoxine)

    Information about Rifampicin + Isoniazid + Ethambutol + Pyrazinamide + Vitamin B6 (Pyridoxine)

    Rifampicin + isoniazid + ethambutol + pyrazinamide + vitamin b6 (pyridoxine) uses

    Rifampicin+Isoniazid+Ethambutol+Pyrazinamide+Vitamin B6 (Pyridoxine) is used in the treatment of tuberculosis.

    How rifampicin + isoniazid + ethambutol + pyrazinamide + vitamin b6 (pyridoxine) works

    This is a combination of five medicines: Rifampicin, isoniazid, ethambutol, pyrazinamide and vitamin B6 (pyridoxine) which treat tuberculosis (TB). Rifampicin works by inactivating a bacterial enzyme (RNA-polymerase) which is required by TB bacteria to make essential proteins and to reproduce, while isoniazid prevents the these bacteria from forming their own protective covering. Together, they kill the bacteria and eradicate the infection. Ethambutol and pyrazinamide, on the other hand work by slowing the growth of these bacteria. Vitamin B6 (pyridoxine) is added to prevent nerve damage which may be a side effect of isoniazid.

    Common side effects of rifampicin + isoniazid + ethambutol + pyrazinamide + vitamin b6 (pyridoxine)

    Nausea, Vomiting, Rash, Fever, Dark colored urine, Sweating, Increased sputum production, Salivation, Teary eyes, Peripheral neuropathy (tingling and numbness of feet and hand), Increased liver enzymes, Jaundice, Increased uric acid level in blood, Visual impairment

    Available Medicine for Rifampicin + Isoniazid + Ethambutol + Pyrazinamide + Vitamin B6 (Pyridoxine)

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    Content on this page was last updated on 19 April, 2018, by Dr. Varun Gupta (MD Pharmacology)