Information about Proguanil

Proguanil uses

Proguanil is used in the treatment of malaria.

How proguanil works

Proguanil is a weak base that reaches high concentration within the malarial parasite and causes accumulation of toxic heme pigment, which kills it.

Common side effects of proguanil

Nausea, Flushing (sense of warmth in the face, ears, neck and trunk), Gastric intolerance, Headache, Indigestion, Loss of appetite, Mouth ulcer, Stomatitis (Inflammation of the mouth), Vomiting, Constipation, Diarrhoea.

Available Medicine for Proguanil

  • ₹70
    Unicure India Pvt Ltd
    1 variant(s)
  • ₹57
    Astrum Healthcare Pvt Ltd
    1 variant(s)

Expert advice for Proguanil

  • Take precautions to reduce the chances of being bitten by mosquitoes while on proguanil treatment.Start taking proguanil one week or at least two days before you enter the malaria area and continue to take it during your stay and for 4 weeks after leaving the malaria area.
  • Take proguanil with a glass of water after meals to decrease the possibility of stomach upset.
  • Tell your doctor immediately if you are pregnant, think you might be pregnant or if you are breast-feeding.

Frequently asked questions for Proguanil


Q. Is atovaquone proguanil the same as malarone?
Atovaquone proguanil is the same as malarone
Q. Is atovaquone-proguanil an antibiotic?
Atovaquone-proguanil is not an antibiotic
Q. What is proguanil and atovaquone?
The drug combination atovaquone/ proguanil is an antimalarial medication used in both the treatment and prevention of malaria.

Content on this page was last updated on 27 March, 2017, by Dr. Varun Gupta (MD Pharmacology)